DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ptpmeg and C33H5.16

DIOPT Version :9

Sequence 1:	NP_001163309.2	Gene:	Ptpmeg / 38059	FlyBaseID:	FBgn0261985	Length:	974	Species:	Drosophila melanogaster
Sequence 2:	NP_501293.3	Gene:	C33H5.16 / 183190	WormBaseID:	WBGene00016382	Length:	341	Species:	Caenorhabditis elegans

Alignment Length:	323	Identity:	82/323 - (25%)
Similarity:	129/323 - (39%)	Gaps:	85/323 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   645 QYELMYRKNPDLAITEARKPANAPKNRYRDISPYDCTRVSLVN-SLTGDYINANYVNMEIPGGAV 708
            ::..|.|.|....:...:|..:..||||:|:...|..||.|.: ....|||:||:|:  .|..|
Worm    54 EFNAMKRFNDFDKMQSFKKAQDHHKNRYKDVGCLDNNRVKLAHPPWPHDYIHANFVS--TPANA- 115

  Fly   709 NRYIATQGPLASTTTDFWRMVQQESSHLLVMLTTVMESGRQKCHQYWPVTGEELQLAEGFSVRCL 773
            .|:|..|.||.:|..|||.|..||....:.||..:||.|.:||.:|: .|.|:.:|......:.:
Worm   116 KRFICAQAPLDNTCADFWYMCLQERVEAIFMLCNLMEKGAKKCSEYY-ATKEKPELVFHEKDQKI 179

  Fly   774 SEKPDETGSFVF--------REFVLKDKHEQRHI---HHMQYLAWPDHCVPSDPNLFLEFTERVR 827
            :.|.:.:|:..|        :|.||..:.....:   .|..::.|||..||
Worm   180 TVKYEASGTVKFVKPTKAVVKETVLIIEGPGGQVLKTTHYHWIDWPDRGVP-------------- 230

  Fly   828 AARNRTLLQEIEESLKQVRLMDADADADENGGLMRERKCAASNGATPEDETPVSTSVHQCISAAN 892
                                                               |...|:.:.:..|.
Worm   231 ---------------------------------------------------PADLSIIELLIKAR 244

  Fly   893 P---PVIVHCSAGIGRTGVLILMDTALALMEAREPVYPLD-IVRTMRDQRACMVQNVSQYRFV 951
            |   |:.|||||||||||.:::::.....:.....:...| |::.:|:||...:|...||.||
Worm   245 PLKGPIAVHCSAGIGRTGSVVMIEYMCEQLLNGNQIEETDKILQKIREQRNNSIQTDHQYLFV 307

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ptpmeg	NP_001163309.2	B41	35..232	CDD:214604
		FERM_N	38..102	CDD:286467
		FERM_M	125..232	CDD:278785
		FERM_C_PTPN4_PTPN3_like	226..320	CDD:270010
		FA	333..369	CDD:285894
		PDZ_signaling	502..589	CDD:238492
		Y_phosphatase	666..955	CDD:278528	78/302 (26%)
		PTPc	668..955	CDD:238006	78/300 (26%)
C33H5.16	NP_501293.3	Y_phosphatase	76..313	CDD:278528	78/301 (26%)
C33H5.16	NP_501293.3	PTPc	77..313	CDD:238006	78/300 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910