DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ptpmeg and C15H7.3

DIOPT Version :9

Sequence 1:	NP_001163309.2	Gene:	Ptpmeg / 38059	FlyBaseID:	FBgn0261985	Length:	974	Species:	Drosophila melanogaster
Sequence 2:	NP_499135.1	Gene:	C15H7.3 / 182639	WormBaseID:	WBGene00007610	Length:	398	Species:	Caenorhabditis elegans

Alignment Length:	298	Identity:	56/298 - (18%)
Similarity:	99/298 - (33%)	Gaps:	97/298 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly   669 KNRYRDISPYDC--TRVSLVNSLTG--DYINANYVNMEIPGGAVNR-YIATQGPLASTT---TDF 725
            ||....|...||  ....||....|  .:|.|  ..:.:|.  .|| .|.||.|..|:.   .||
Worm   148 KNNMHKIRAPDCPIPEEKLVKLTNGPESFICA--AKITVPD--FNRTMILTQVPDLSSAPDIADF 208

  Fly   726 WRMVQQESSHLLVMLTTVME----------SGRQKCHQYWPVTGEELQLAEGFSVRCLSEKPDET 780
            |||:.|||...:|:....:|          ||....:....|..::::.|.|.:..||...||..
Worm   209 WRMIHQESIASVVIAVMPLEVTLQQILPLLSGTYSTYGKMFVNNKKVESAVGMTEYCLEIFPDGC 273

  Fly   781 GSFVFREFVLKDKHEQRHIHHMQYLAWPDHCVPSDPNLFLEFTERVRAARNRTLLQEIEESLKQV 845
            .:.:.....        |:|:     |                   |..|...::.::..::::|
Worm   274 SNSLLTTVY--------HLHN-----W-------------------RQKRGLEVVTDLVATMEKV 306

  Fly   846 RLMDADADADENGGLMRERKCAASNGATPEDETPVSTSVHQCISAANPPVIVHCSAGIGRTGVLI 910
                                                       ...|...::....|.||.|.::
Worm   307 -------------------------------------------MKVNDNTVLMSMNGTGRAGTML 328

  Fly   911 LMDTALALMEAREPVYPLDIVRTMRDQRACMVQNVSQY 948
            .:.||:..::..:.|...:.:.::|.:|..:|.|:.|:
Worm   329 TLFTAMLQVQKGKEVNAKETLASLRAERCGIVDNIDQF 366

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ptpmeg	NP_001163309.2	B41	35..232	CDD:214604
		FERM_N	38..102	CDD:286467
		FERM_M	125..232	CDD:278785
		FERM_C_PTPN4_PTPN3_like	226..320	CDD:270010
		FA	333..369	CDD:285894
		PDZ_signaling	502..589	CDD:238492
		Y_phosphatase	666..955	CDD:278528	56/298 (19%)
		PTPc	668..955	CDD:238006	56/298 (19%)
C15H7.3	NP_499135.1	PTPc	131..374	CDD:214550	56/298 (19%)
C15H7.3	NP_499135.1	PTPc	148..374	CDD:304379	56/298 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910