Protein Alignment Ptpmeg and magi-1

DIOPT Version :9

• Sequence 1: NP_001163309.2
• Gene: Ptpmeg / 38059
• FlyBaseID: FBgn0261985
• Length: 974
• Species: Drosophila melanogaster
• Sequence 2: NP_001255577.1
• Gene: magi-1 / 178107
• WormBaseID: WBGene00010444
• Length: 1054
• Species: Caenorhabditis elegans
• Alignment Length: 486
• Identity: 98/486 - (20%)
• Similarity: 177/486 - (36%)
• Gaps: 116/486 - (23%)

  Fly   359 HKVFVRSPSKRLLGAAGGV----GTSGSSGGTPMQQ-HSGSESANSHNNGKPAGAGTILTITKTS 418
            |...|....:|.:|..|.:    |:..:...||... ..|....|..::..|..       .::.
 Worm   591 HTQLVDMLRERPIGYRGKLVVKRGSPKTRSRTPSAAFRYGEPQTNMMDSAAPLP-------VRSK 648

  Fly   419 RPHDNKVTSKEADSMPRKAWEQQ---SDEYDIQLDVGFIEQCTRRFESASP-SPMPPAYSS-GQH 478
            .|.:.:.:..|.|...|...::|   :.|::             ...||.| |.|.|:.:: |..
 Worm   649 TPAERQTSRTEEDQNVRNTLQRQPAVTSEWE-------------GMSSAIPASRMRPSSTTLGFA 700

  Fly   479 SPILLPTTIADAVGHQQPESGSDLITIRLQADEQGRYGFNVKGGVDLSLPVQVSKVVPHTPADRC 543
            :|..:|.:       |..:..|||||:.|.....| :||.:.|||:...|:.|.::|....|:.
 Worm   701 TPNYIPLS-------QYNQKPSDLITVSLIRKPVG-FGFRLLGGVESKTPLSVGQIVIGGAAEE- 756

  Fly   544 TPRVCEGDEVLMINGRDVHGLRHEQVVAMIRDCRHQASGELLLTVRPQRSAPL----LLEEEPLY 604
            ..|:.||||::.|:|.:|.|..|.:.|.:: :...|.....|:..||.|:.|.    |....|..
 Worm   757 DGRLQEGDEIVEIDGHNVEGASHSEAVVLL-EAAAQNKHVKLIVRRPSRTDPARRGSLNSAGPSG 820

  Fly   605 QYVPESDEIGSHSNLLDGDALFTQSLLLLSDGLASGALLAQ------------------------ 645
            .|     ::..|.|..||     ...:|:|....:|:.:.|
 Worm   821 SY-----DVLLHRNENDG-----FGFVLMSSQHKNGSTVGQIQPGSPAARCGRLSVGDRVIAVNG 875

  Fly   646 YELMYRKNPD---------LAITEARKPANAPKNRYRDISPYDCTRVSLVNSLTGDYINANY--- 698
            .:::...:||         |::    :...||.|....:.|.....:....::.|.| .:||
 Worm   876 IDILSLSHPDTISLIKDSGLSV----RLTIAPPNTAGPVLPMVSATLGRNFTMNGHY-ESNYGLP 935

  Fly   699 -------------VNMEIPGGAVNRYIATQGPLASTTTD-----FWRMVQ--QESSHLLVMLTTV 743
                         ..:...|.::|..::..|.|...|.:     |...::  ||...:.:.:..:
 Worm   936 PPPPSVYEKHPPPSYLAFDGLSINDRMSMNGNLIDVTLERGTKGFGFSIRGGQEFGSMPLFVLRI 1000

  Fly   744 MESGRQKCHQYWPVTGEELQLAEGFSVRCLS 774
            .:.|..|......| |::|....|.|.:.:|
 Worm  1001 ADDGPAKADGRLQV-GDQLTTINGQSTKGMS 1030

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ptpmeg	NP_001163309.2	B41	35..232	CDD:214604
		FERM_N	38..102	CDD:286467
		FERM_M	125..232	CDD:278785
		FERM_C_PTPN4_PTPN3_like	226..320	CDD:270010
		FA	333..369	CDD:285894	2/9 (22%)
		PDZ_signaling	502..589	CDD:238492	27/86 (31%)
		Y_phosphatase	666..955	CDD:278528	24/132 (18%)
		PTPc	668..955	CDD:238006	23/130 (18%)
magi-1	NP_001255577.1	NK	180..>244	CDD:302627
		WW	263..293	CDD:238122
		WW	294..323	CDD:278809
		PDZ	421..510	CDD:214570
		PDZ_signaling	535..600	CDD:238492	2/8 (25%)
		PDZ_signaling	717..800	CDD:238492	27/85 (32%)
		PDZ_signaling	822..902	CDD:238492	12/93 (13%)
		PDZ_signaling	968..1049	CDD:238492	13/64 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910