Protein Alignment Ptpmeg and ptp-5.1

DIOPT Version :9

• Sequence 1: NP_001163309.2
• Gene: Ptpmeg / 38059
• FlyBaseID: FBgn0261985
• Length: 974
• Species: Drosophila melanogaster
• Sequence 2: NP_500733.2
• Gene: ptp-5.1 / 177291
• WormBaseID: WBGene00016053
• Length: 482
• Species: Caenorhabditis elegans
• Alignment Length: 607
• Identity: 110/607 - (18%)
• Similarity: 191/607 - (31%)
• Gaps: 211/607 - (34%)

  Fly   385 GTPMQQHS----GSESANSHNNG----KPAGAGTILTITKTSRPHDNKVTSKEADSMPRKAWEQQ 441
            ||..::.|    |...:.:..||    ||.|..|... .|.||.:|:|....|..:..:||
 Worm     6 GTKNKKRSKNKDGKLMSTASRNGDEATKPNGTKTSKK-RKPSRGNDDKGREPEPTAQSKKA---- 65

  Fly   442 SDEYDIQLDVGFIEQCTRRFESASPSPMPPAYSSGQHSPIL----------LPTTIADAVGHQQP 496
                         ::...:.:|.:||   ||.|.|....:.          .|..||.:|
 Worm    66 -------------KKMKPKRDSKAPS---PALSPGPREQLSDQKKTVEDDPPPAPIATSV----- 109

  Fly   497 ESGSDLITIRLQADEQGRYGFNVKGGVDLSLPVQVSKVVPHTPADRCTPRVCEGDEVLMINGRDV 561
             ||:                              |:..|...||               |...:|
 Worm   110 -SGT------------------------------VTSTVNAMPA---------------ILSSEV 128

  Fly   562 HGLRHEQVVAMIRDCRHQASGELLLTVRPQRSAPLLLEEEPLYQYVPESDEIGSHSNLLDGDA-- 624
            ...:.::|.:|                :..:.||....:.|:           ||...:.|:|
 Worm   129 SNKQPKEVNSM----------------KKTKGAPNSTTDTPV-----------SHKTSITGNADK 166

  Fly   625 -LFTQSLLLLSDGLASGALLAQYELMYRKNPDLAITEARKPANAPKNRYRDISPYDCTRVSLVNS 688
             :.........|.:....:...:|.:.....|:........||:..|:.......|...:.:...
 Worm   167 WVGEDVAKTWMDSIDLAEVKKDFEKLQTMKIDIDKDCKTWKANSKLNQSEHFPALDSNLLKIEKG 231

  Fly   689 LTGDYINANYVNMEIPGGAVNRYIATQGPLASTTTDFWRMVQQESSHLLVMLTTVMESGRQKCHQ 753
                |:|.::|  |:|.|. |.:|. |.|:..|...||:.|..:      .:|::......:..:
 Worm   232 ----YVNISHV--EVPLGR-NVHIG-QFPVKDTEETFWKAVFDK------RITSIDVLVGDEPIE 282

  Fly   754 YWPVTGEELQLAEGFSVRCLSEKP-----DETGSFVFREFVLKDKHEQRHIHHMQYLA-WPDHCV 812
            ::|...|:.   :.:....::.:.     ||.  |.|...||........|.::.... |....|
 Worm   283 FFPKKAEDY---KNYGQMWINNRKVEHVIDEV--FRFSIEVLPHGCSNSIICNVTVFGNWKVDSV 342

  Fly   813 PSDPNLFLEFTERVRAARNRTLLQEIEESLKQVRLMDADADADENGGLMRERKCAASNGATPEDE 877
            |            |:.|      ..|:|:|            ..|..|::          ||.|:
 Worm   343 P------------VKQA------IAIKEAL------------GLNYFLLK----------TPADD 367

  Fly   878 TPVSTSVHQCISAANPPVIVHCSAGIGRTGVLILMDTALALMEAR--EPVYPLDIVRTMRDQRAC 940
            ..:..|.|                |.||.|..:.:..|:..::.:  ||.. .|||:::|.||..
 Worm   368 NAMIISPH----------------GAGRAGYFLALAVAVHTIDTKIAEPNI-ADIVKSIRTQRPR 415

  Fly   941 MVQNVSQYRFVCECICAAYMKI 962
            .|.:..||       |:.|:.:
 Worm   416 AVDSFCQY-------CSLYISL 430

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ptpmeg	NP_001163309.2	B41	35..232	CDD:214604
		FERM_N	38..102	CDD:286467
		FERM_M	125..232	CDD:278785
		FERM_C_PTPN4_PTPN3_like	226..320	CDD:270010
		FA	333..369	CDD:285894
		PDZ_signaling	502..589	CDD:238492	8/86 (9%)
		Y_phosphatase	666..955	CDD:278528	58/296 (20%)
		PTPc	668..955	CDD:238006	57/294 (19%)
ptp-5.1	NP_500733.2	PTPc	185..432	CDD:214550	63/329 (19%)
		PTPc_motif	334..432	CDD:214649	33/161 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910