DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ptpmeg and F47B3.7

DIOPT Version :9

Sequence 1:	NP_001163309.2	Gene:	Ptpmeg / 38059	FlyBaseID:	FBgn0261985	Length:	974	Species:	Drosophila melanogaster
Sequence 2:	NP_491276.1	Gene:	F47B3.7 / 171983	WormBaseID:	WBGene00018531	Length:	374	Species:	Caenorhabditis elegans

Alignment Length:	352	Identity:	96/352 - (27%)
Similarity:	151/352 - (42%)	Gaps:	97/352 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   633 LSDGLASGALLAQYELMYRKNPDLAITEARKPANAPKNRYRDISPYDCTRVSL-VNSLTGDYINA 696
            |:.|::.  |..::..:..|||::.: :|.| :|..||||.||...:.|||.| .:..:.|||:|
Worm    61 LNKGVSK--LRDEFSEVANKNPNVPV-DAFK-SNPEKNRYTDIKCIEKTRVILTTDGASSDYIHA 121

  Fly   697 NYVNMEIPGGAVNRYIATQGPLASTTTDFWRMVQQESSHLLVMLTTVMESGRQKCHQYWP-VTGE 760
            |||.:.|   ...::|.||||..||..|||.||.|::...::||..|:|..|.||.|||| |.|:
Worm   122 NYVGISI---KPKKFICTQGPKDSTIYDFWAMVIQDNVESIIMLCKVIELARVKCEQYWPAVEGQ 183

  Fly   761 -ELQLAEG-------FSVRCLSEKPDETGSFVFR-EFVLKDKHEQRHIHHMQYLAWPDHCVPSDP 816
             ...:::|       ..|..||  ||:....|.. |.|...|  .|.|.|.|:..||||..|
Worm   184 TNTYVSKGHTITINNLGVGTLS--PDDDFINVTNLELVWAGK--TRSITHYQWTNWPDHGAP--- 241

  Fly   817 NLFLEFTERVRAARNRTLLQEIEESLKQVRLMDADADADENGGLMRERKCAASNGATPEDETPVS 881
                                                                          |::
Worm   242 --------------------------------------------------------------PIN 244

  Fly   882 TSVHQCISAAN---PPVIVHCSAGIGRTGVLI----LMDTALALMEAREPVYPLDIVRTMRDQRA 939
            ......|.|.|   .||:||||||:||:|.::    :||..:..:..::   ...:|..:|:||.
Worm   245 MGAINLIEAVNYDTNPVVVHCSAGVGRSGTIVGISLIMDKMIQGINCKD---MKKLVEEIRNQRH 306

  Fly   940 CMVQNVSQYRFVCECICAAYMKISRSS 966
            ..:|..:||.::...:...::::.:.:
Worm   307 YAIQTEAQYMYIHRVLLEYFLELHKET 333

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ptpmeg	NP_001163309.2	B41	35..232	CDD:214604
		FERM_N	38..102	CDD:286467
		FERM_M	125..232	CDD:278785
		FERM_C_PTPN4_PTPN3_like	226..320	CDD:270010
		FA	333..369	CDD:285894
		PDZ_signaling	502..589	CDD:238492
		Y_phosphatase	666..955	CDD:278528	88/306 (29%)
		PTPc	668..955	CDD:238006	87/304 (29%)
F47B3.7	NP_491276.1	Y_phosphatase	90..324	CDD:278528	88/308 (29%)
F47B3.7	NP_491276.1	PTPc	92..324	CDD:238006	87/306 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910