DRSC/TRiP Functional Genomics Resources

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Protein Alignment Ptpmeg and F47B3.7

DIOPT Version :9

Sequence 1:NP_001163309.2 Gene:Ptpmeg / 38059 FlyBaseID:FBgn0261985 Length:974 Species:Drosophila melanogaster
Sequence 2:NP_491276.1 Gene:F47B3.7 / 171983 WormBaseID:WBGene00018531 Length:374 Species:Caenorhabditis elegans


Alignment Length:352 Identity:96/352 - (27%)
Similarity:151/352 - (42%) Gaps:97/352 - (27%)


- Green bases have known domain annotations that are detailed below.


  Fly   633 LSDGLASGALLAQYELMYRKNPDLAITEARKPANAPKNRYRDISPYDCTRVSL-VNSLTGDYINA 696
            |:.|::.  |..::..:..|||::.: :|.| :|..||||.||...:.|||.| .:..:.|||:|
 Worm    61 LNKGVSK--LRDEFSEVANKNPNVPV-DAFK-SNPEKNRYTDIKCIEKTRVILTTDGASSDYIHA 121

  Fly   697 NYVNMEIPGGAVNRYIATQGPLASTTTDFWRMVQQESSHLLVMLTTVMESGRQKCHQYWP-VTGE 760
            |||.:.|   ...::|.||||..||..|||.||.|::...::||..|:|..|.||.|||| |.|:
 Worm   122 NYVGISI---KPKKFICTQGPKDSTIYDFWAMVIQDNVESIIMLCKVIELARVKCEQYWPAVEGQ 183

  Fly   761 -ELQLAEG-------FSVRCLSEKPDETGSFVFR-EFVLKDKHEQRHIHHMQYLAWPDHCVPSDP 816
             ...:::|       ..|..||  ||:....|.. |.|...|  .|.|.|.|:..||||..|   
 Worm   184 TNTYVSKGHTITINNLGVGTLS--PDDDFINVTNLELVWAGK--TRSITHYQWTNWPDHGAP--- 241

  Fly   817 NLFLEFTERVRAARNRTLLQEIEESLKQVRLMDADADADENGGLMRERKCAASNGATPEDETPVS 881
                                                                          |::
 Worm   242 --------------------------------------------------------------PIN 244

  Fly   882 TSVHQCISAAN---PPVIVHCSAGIGRTGVLI----LMDTALALMEAREPVYPLDIVRTMRDQRA 939
            ......|.|.|   .||:||||||:||:|.::    :||..:..:..::   ...:|..:|:||.
 Worm   245 MGAINLIEAVNYDTNPVVVHCSAGVGRSGTIVGISLIMDKMIQGINCKD---MKKLVEEIRNQRH 306

  Fly   940 CMVQNVSQYRFVCECICAAYMKISRSS 966
            ..:|..:||.::...:...::::.:.:
 Worm   307 YAIQTEAQYMYIHRVLLEYFLELHKET 333

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
PtpmegNP_001163309.2 B41 35..232 CDD:214604
FERM_N 38..102 CDD:286467
FERM_M 125..232 CDD:278785
FERM_C_PTPN4_PTPN3_like 226..320 CDD:270010
FA 333..369 CDD:285894
PDZ_signaling 502..589 CDD:238492
Y_phosphatase 666..955 CDD:278528 88/306 (29%)
PTPc 668..955 CDD:238006 87/304 (29%)
F47B3.7NP_491276.1 Y_phosphatase 90..324 CDD:278528 88/308 (29%)
PTPc 92..324 CDD:238006 87/306 (28%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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