Protein Alignment Ptpmeg and Y71F9AL.4

DIOPT Version :9

• Sequence 1: NP_001163309.2
• Gene: Ptpmeg / 38059
• FlyBaseID: FBgn0261985
• Length: 974
• Species: Drosophila melanogaster
• Sequence 2: NP_491071.1
• Gene: Y71F9AL.4 / 171861
• WormBaseID: WBGene00022110
• Length: 557
• Species: Caenorhabditis elegans
• Alignment Length: 580
• Identity: 118/580 - (20%)
• Similarity: 194/580 - (33%)
• Gaps: 215/580 - (37%)

  Fly   423 NKVTSKEADSMPRKAWEQQSDEYDIQLD-VGFIEQCTRRFESASPSPMPPAYSSGQHSPILLPTT 486
            :|.|.|:.|...:...:::.||....|: ...:||.. ..|:...|.:.|..::|:..|
 Worm    67 SKPTGKKRDEKRKSVSKEEDDEKPAPLERQRSVEQIA-NMENTPESVLKPPDNNGKPKP------ 124

  Fly   487 IADAVGHQQPESGSDLITIRLQADEQGRYGFNVKGGVDLSLPVQVSKVVPHTPADRCTPRVCEGD 551
                 .|::.                                   :||..:           :.|
 Worm   125 -----SHEKD-----------------------------------AKVKKN-----------DDD 138

  Fly   552 EVLMINGRDVHGLRHEQVVAMIRDCRHQASGELLLTVRPQRSAPLLLEEEPLYQYVPESDEIGSH 616
            :.|....:|:.....||...||   :..||..::.|  ||             |...|...:|:
 Worm   139 DDLGSEKKDLEPKEKEQRAEMI---KKWASAVMMST--PQ-------------QLTKEYKAVGN- 184

  Fly   617 SNLLDGDALFTQSLLLLSDGLASGALLAQYELMYRKNPDLAITEARKPANAPKNRYRDISPYDCT 681
                           ::||...:..|         |..||             |||.:|..:|..
 Worm   185 ---------------IVSDSECTAFL---------KFKDL-------------NRYPNIQCWDRG 212

  Fly   682 RVSLVNSLTGD---YINANYVNM-EIPGGAVNRYIATQGPLASTTTDFWRMVQQESSHLLVMLTT 742
            |.    :|.||   ||:||:|.: ..|    .|::.||||:.:|.|.||:|.....|..::||..
 Worm   213 RF----TLAGDENFYIHANFVKICTKP----ERFVCTQGPMENTCTHFWQMALSLGSTSIIMLCG 269

  Fly   743 VMESGRQKCHQY-WPVTG-EELQLAEGFSVRC----LSEKPDETGSFVFREFVLKDKHEQRHIHH 801
            .:|.|.:||.:| ..:.| ..|:....::..|    :..|..:..:....:.|:|...::..::|
 Worm   270 FVEDGSEKCAKYISDIVGFVNLEDHRVYTEYCTEIEIGGKSKDKITHRVLKVVVKATGQESKLNH 334

  Fly   802 MQYLAWPDHCVPSDPNLFLEFTERVRAARNRTLLQEIEESLKQVRLMDADADADENGGLMRERKC 866
            .|:.:||||.:|...:..|                         ||:.|         :.:::|
 Worm   335 YQWASWPDHGMPDSCDTAL-------------------------RLLSA---------VKKDKK- 364

  Fly   867 AASNGATPEDETPVSTSVHQCISAANPPVIVHCSAGIGRTGVLILMDTALALMEAREPVYPLDIV 931
                                       |||.|||||:||||.|.|:::.:|.:.........|..
 Worm   365 ---------------------------PVIAHCSAGVGRTGTLALIESMIAALRHPRKQNVKDSF 402

  Fly   932 RTMRDQRACMVQNVSQYRFVCECIC--------------------AAYMKISRSSAAIND 971
            ..:|..||..||...||.:...|:.                    ..|.||......|.|
 Worm   403 VLLRKDRARSVQTFPQYVYALRCVLEFLYSKGLYKRNEQEWTKFKETYAKIKAKKLKIKD 462

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ptpmeg	NP_001163309.2	B41	35..232	CDD:214604
		FERM_N	38..102	CDD:286467
		FERM_M	125..232	CDD:278785
		FERM_C_PTPN4_PTPN3_like	226..320	CDD:270010
		FA	333..369	CDD:285894
		PDZ_signaling	502..589	CDD:238492	12/86 (14%)
		Y_phosphatase	666..955	CDD:278528	74/298 (25%)
		PTPc	668..955	CDD:238006	74/296 (25%)
Y71F9AL.4	NP_491071.1	PTPc	177..428	CDD:214550	83/358 (23%)
		PTPc	199..428	CDD:238006	77/311 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910