Protein Alignment Ptpmeg and ptprjb.1

DIOPT Version :9

• Sequence 1: NP_001163309.2
• Gene: Ptpmeg / 38059
• FlyBaseID: FBgn0261985
• Length: 974
• Species: Drosophila melanogaster
• Sequence 2: XP_017209718.2
• Gene: ptprjb.1 / 101883510
• ZFINID: ZDB-GENE-090304-1
• Length: 1104
• Species: Danio rerio
• Alignment Length: 575
• Identity: 144/575 - (25%)
• Similarity: 212/575 - (36%)
• Gaps: 155/575 - (26%)

  Fly   414 ITKTSRPH--DNKVTSKEADSMPRKAWEQQSDEYDIQLDVGFIEQCTRRFESASPSPMPPAYSSG 476
            |:..::|:  .|...||...|.....|...|...|..|....:::.|.|..:.:...:..
Zfish   649 ISSFTKPNVVSNLTASKVTTSSVTLHWNAPSGPIDYYLVEWSVQRSTDRRTNETFYVITD----- 708

  Fly   477 QHSPILLPTTIADAVGHQQPESG---SDLITIRLQAD-EQGRYGFNVKG---GVDLSLPVQVSKV 534
                 |:|.|..:.  |....:|   |:|:.:.:..| |.|....|..|   |:.|:|...::.:
Zfish   709 -----LMPATKYEI--HVSAVTGGIKSELVFLTVLTDVEAGPTSTNNTGMIVGIVLTLICLIAAI 766

  Fly   535 VPHTPADRCTPRVCEGDEVLMINGRDVHGLRHEQVVAMIRDCRHQASGELLLTVRPQRSAPLLLE 599
            :..               |...:.|.......:..|.||||....|                 |:
Zfish   767 ILF---------------VFFYSRRQSKKQYPDIPVHMIRDQTKNA-----------------LK 799

  Fly   600 EEPLYQYVPESDEIGSHSNLLDGDALFTQSLLLLSDGLASGALLAQYELMYRKNPDLAITEARKP 664
            .|...:|...        |..|.:..|.:                :||.:.......:...|...
Zfish   800 VEDYEEYFKR--------NSADSNCGFAE----------------EYEELKSVGTQQSKAAALAI 840

  Fly   665 ANAPKNRYRDISPYDCTRVSLVNSLTG----DYINANYVNMEIPG-GAVNRYIATQGPLASTTTD 724
            .|..||||.::.|||.:||.|  |:.|    ||||||:|    || .:...:||.||||..|..:
Zfish   841 ENKAKNRYSNVLPYDASRVKL--SMCGSPFDDYINANHV----PGYNSRKEFIAAQGPLPVTLNE 899

  Fly   725 FWRMVQQESSHLLVMLTTVMESGRQKCHQYWPVTGEELQLAEGFSVRCLSEKPDETGSFVFREFV 789
            ||||:.:::.:.:||||...|.||.||.:|||......   ...||...||  .|...:..|:|.
Zfish   900 FWRMIWEKNVYTIVMLTKCNEMGRVKCEKYWPSATSHY---NNISVTTTSE--IELDDWTIRDFR 959

  Fly   790 LKD--KHEQRHIHHMQYLAWPDHCVPSDPNLFLEFTERVRAARNRTLLQEIEESLKQVRLMDADA 852
            :|:  ..|.|::....:.|||||.||....:.::|...||            |.:.|.
Zfish   960 IKNVKTAETRYVRQFHFTAWPDHGVPETTEILIDFRHLVR------------EHMDQY------- 1005

  Fly   853 DADENGGLMRERKCAASNGATPEDETPVSTSVHQCISAANPPVIVHCSAGIGRTGVLILMDTALA 917
                                                 :.:.|.:||||||:||||..|.:|....
Zfish  1006 -------------------------------------SRHSPTVVHCSAGVGRTGTFIAIDHLSF 1033

  Fly   918 LMEAREPVYPLDIVRTMRDQRACMVQNVSQYRFVCECICAAYMKISRSSAAINDD 972
            .:|....|....||..||..||.|||...||.::.:|   || .:.||....|.|
Zfish  1034 QIERDSMVDIYGIVHDMRMHRALMVQTEDQYVYLHQC---AY-DLIRSRTGTNVD 1084

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ptpmeg	NP_001163309.2	B41	35..232	CDD:214604
		FERM_N	38..102	CDD:286467
		FERM_M	125..232	CDD:278785
		FERM_C_PTPN4_PTPN3_like	226..320	CDD:270010
		FA	333..369	CDD:285894
		PDZ_signaling	502..589	CDD:238492	17/90 (19%)
		Y_phosphatase	666..955	CDD:278528	93/295 (32%)
		PTPc	668..955	CDD:238006	92/293 (31%)
ptprjb.1	XP_017209718.2	NupH_GANP	450..>493	CDD:318883
		FN3	568..653	CDD:238020	1/3 (33%)
		FN3	655..729	CDD:238020	16/85 (19%)
		PTPc	817..1071	CDD:214550	98/339 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910