DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ptpmeg and mpp7b

DIOPT Version :9

Sequence 1:	NP_001163309.2	Gene:	Ptpmeg / 38059	FlyBaseID:	FBgn0261985	Length:	974	Species:	Drosophila melanogaster
Sequence 2:	XP_021324128.1	Gene:	mpp7b / 101882129	ZFINID:	ZDB-GENE-141212-293	Length:	298	Species:	Danio rerio

Alignment Length:	158	Identity:	35/158 - (22%)
Similarity:	62/158 - (39%)	Gaps:	32/158 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   459 RRFESASPSPMPPAYSSGQHSPILLPTTIADAVGHQQPESGSDLITIRLQADEQGRYGFNVKGGV 523
            :||:...| |:||           ||..         .|...|.|.|......|...|..:|..
Zfish    74 KRFDPRLP-PLPP-----------LPDC---------NEEDEDSIKIVCLVKNQEPLGATIKRD- 116

  Fly   524 DLSLPVQVSKVVPHTPADRCTPRVCEGDEVLMINGRDVHGLRHEQVVAMIRDCRHQASGELLLTV 588
            :.|..:.|::|:....||| :..:.|||.:..:||..|.....::::.::.    ::.|.:...|
Zfish   117 ESSGAIIVARVMRGGAADR-SGLIHEGDMLKEVNGVPVEDKNLQEIIPILA----KSEGAVTFKV 176

  Fly   589 RPQRSAPLLLEE-----EPLYQYVPESD 611
            .|..:..|...:     ..|:.|.|::|
Zfish   177 VPGTNEELETNDTQVFVRALFDYDPQAD 204

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ptpmeg	NP_001163309.2	B41	35..232	CDD:214604
		FERM_N	38..102	CDD:286467
		FERM_M	125..232	CDD:278785
		FERM_C_PTPN4_PTPN3_like	226..320	CDD:270010
		FA	333..369	CDD:285894
		PDZ_signaling	502..589	CDD:238492	18/86 (21%)
		Y_phosphatase	666..955	CDD:278528
		PTPc	668..955	CDD:238006
mpp7b	XP_021324128.1	L27	31..74	CDD:308467	35/158 (22%)
		PDZ	97..179	CDD:214570	19/87 (22%)
		SH3_MPP	192..252	CDD:212796	4/13 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910