Protein Alignment Ptpmeg and frmd4ba

DIOPT Version :9

• Sequence 1: NP_001163309.2
• Gene: Ptpmeg / 38059
• FlyBaseID: FBgn0261985
• Length: 974
• Species: Drosophila melanogaster
• Sequence 2: XP_009300910.2
• Gene: frmd4ba / 100333566
• ZFINID: ZDB-GENE-130412-1
• Length: 1028
• Species: Danio rerio
• Alignment Length: 1013
• Identity: 197/1013 - (19%)
• Similarity: 328/1013 - (32%)
• Gaps: 329/1013 - (32%)

  Fly    38 VLFLDDITHTFRIEKRAKGSELLDQVFQYLELSERDYFGLLFPQKPGDVVRWVDAQKQFKKQCSS 102
            ||.|||......::.:....:|||.|..:..|.|:||||:.|..:.|. .:|:...::.
Zfish    63 VLLLDDRQLELLVQPKLLSRDLLDLVSSHFNLKEKDYFGISFTDERGQ-KKWLQLDRRV------ 120

  Fly   103 VSLDND----AVPL-LEFRVKFFVSDPSRLQEEFTRYQFYLQIKRNILLGKLPCSSNTQCLLASY 162
              ||:|    :.|| |:|:|:|::...:.|::..|...|:...|.::....:...|.....||:|
Zfish   121 --LDHDFNKKSGPLELKFQVRFYIESVAYLKDATTVELFFRNAKISVYNENIEVESEIVFKLAAY 183

  Fly   163 TVQSELGDF-------NALEHQPGYLSGMQLLCDQTTEAERKVGELHKLHRGQLPADAEYNYLEH 220
            |:|...||:       :||:..|.:.:.:.......|..|.||.|.:|..:|.....|...||..
Zfish   184 TLQEANGDYTSDESTRSALKKLPAFPTAVLKEHPSLTFCEDKVIERYKKLKGLSRGQAIVRYLTL 248

  Fly   221 AKRLELYGIDLHRATDSNGKELQLGVS--AVGLLVFQHSLRV-NTFSWSKMVKVSFKRKDFFIQL 282
            .:.|..||:..::..|..|....||:|  .:|....|..|:. ..|.|.::..:.|:.|.|.:::
Zfish   249 VESLPAYGVHYYKVKDKQGLPWWLGISYKGIGQYDLQDKLKPRKLFLWKQLENLYFREKKFAVEV 313

  Fly   283 RREPSENYDTLLGFGMS---------SHKHAKALWKSCVEHHSFFRLKRPHRLSRFLNISLGSKF 338
             .:|.....:...||.|         ||...|.:|...:..|.|:..::..:.......|||.
Zfish   314 -NDPQRRTASRRTFGQSGQAIHTWYASHSLIKTIWVMAISQHQFYLDRKQSKAKITTARSLGD-- 375

  Fly   339 YYSGRTELQAVQESKQRGRIHKVFVRSPSKRLLGAAGGVGTSGSSGGTPMQQHSGSESANSHNNG 403
            .....||..|.:.||      .|.:.|..|.::.:.|.:.:|.|:.....::....:.|...:..
Zfish   376 IAMDLTETGAPRNSK------LVSMESKDKLIMASNGSLVSSNSADNDVNEEQKKEKIAELKDKQ 434

  Fly   404 KPAGAGTILTITKTSRPHDNKVTSKEAD-------SMPRKAWEQ------------QSDE---YD 446
            :     .|..|.........|:..:||:       ..|..:.|:            :.|:   ||
Zfish   435 E-----KIKQILALKEEELKKMCLREAELTGVLPKEFPLASGEKPPTIRRRVGTAFKLDDLFPYD 494

  Fly   447 IQLDVGFIEQCTRRFESASPSPMPPAYSSGQHSPILLPTTIADA---VGHQQPESGSDL------ 502
                   .:.|.|..||.                ..|...|.:|   :.|:. |.|..:
Zfish   495 -------ADPCLRNLESC----------------FALQKKIVEAARKLAHEN-ELGKTVKKKRRR 535

  Fly   503 ----ITIRLQADEQGRYGFNVKGGVDLSLPVQVSKVVPHTPADRCTPRVCEGDEVLMINGRDVHG 563
                .|.:|||.|.....:.||.|.:   |.|.:.|:   .||                  ||:
Zfish   536 NLLDATKKLQAIENEINDYRVKIGKE---PTQRASVI---IAD------------------DVN- 575

  Fly   564 LRHEQVVAMIRDCRHQASGELLLTVRPQRSAPLLLEEEPLYQYVPESDEIGS-----HSNLLD-- 621
                  :..:.||.:....|   ..:.|||..:        ||.|..:..||     ||:.||
Zfish   576 ------LDSLSDCLNLDDDE---PSQRQRSRSV--------QYSPLPNSSGSFTASYHSDQLDHA 623

  Fly   622 -----------------------GDALFT------QSLLLLSDGLA------------------- 638
                                   .|||.|      |.|...||..:
Zfish   624 NDDYSNCSRLNYAEVQEPVAYIHEDALSTHSSPYRQPLRQPSDSRSMPPTPQLPRNAYSSIQLST 688

  Fly   639 -----SGALLAQYELMYRKNPDLAI-------------------------TEARKPANAPKNRYR 673
                 ||:|.:|.:.:....|...:                         .|...|.:..|||:|
Zfish   689 LYRQRSGSLESQSQFLTESEPSEPVFISAPRRSNSTELLDDGSSYTSQSSVEYSAPHSRAKNRHR 753

  Fly   674 ----DISPYDCTRVSLVNSLTGDYI---------------------------------------- 694
                :|.....:..:|..:.|..||
Zfish   754 RRQGNIYANTGSMPNLAQNDTRGYISQSQHPQTTTAYYVTGYPRYIEPEVYPNGPYMYESEMEGH 818

  Fly   695 ------------NANYVNMEIPGGAVNRYIATQGPLASTTTDFWRMVQQESSHLLVMLTTVMESG 747
                        :.||...|:.|.:.|.|...:.|.....:....:|:.      :....|:|..
Zfish   819 YNVNPSYHRHEPHGNYAQDEMDGLSHNLYATLRPPRNRPPSRNENLVKN------MQRAEVVEHL 877

  Fly   748 RQKCHQYWPVTGEELQLA--EGFSVRCLSE---KPDETGSF--------------VFREFVLKDK 793
            |...::.....|.:...|  :..:.|.:|.   :.|.|.|:              ...|:.:...
Zfish   878 RGWYNRQHKPQGYDAYRAPQQSLNYRTMSTSYVRSDSTASYSTVGSGNWHGRPVMAMSEYEMPLA 942

  Fly   794 HEQRH----IHHMQYL--------AWPDHCVPSDPNLF 819
            |.|.:    :||...|        ||  || |:.|..:
Zfish   943 HHQSYGYNTVHHSHPLHSSSHPKRAW--HC-PASPQYY 977

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ptpmeg	NP_001163309.2	B41	35..232	CDD:214604	55/205 (27%)
		FERM_N	38..102	CDD:286467	18/63 (29%)
		FERM_M	125..232	CDD:278785	28/113 (25%)
		FERM_C_PTPN4_PTPN3_like	226..320	CDD:270010	25/105 (24%)
		FA	333..369	CDD:285894	10/35 (29%)
		PDZ_signaling	502..589	CDD:238492	18/96 (19%)
		Y_phosphatase	666..955	CDD:278528	39/241 (16%)
		PTPc	668..955	CDD:238006	39/239 (16%)
frmd4ba	XP_009300910.2	B41	61..260	CDD:214604	55/205 (27%)
		FERM_C_FRMD4A_FRMD4B	256..366	CDD:270012	24/110 (22%)
		DUF3338	395..527	CDD:314652	25/160 (16%)
		DMP1	<586..750	CDD:311295	28/174 (16%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910