Protein Alignment Ptpmeg and farp1

DIOPT Version :9

• Sequence 1: NP_001163309.2
• Gene: Ptpmeg / 38059
• FlyBaseID: FBgn0261985
• Length: 974
• Species: Drosophila melanogaster
• Sequence 2: XP_017211441.1
• Gene: farp1 / 100329707
• ZFINID: ZDB-GENE-070424-163
• Length: 1041
• Species: Danio rerio
• Alignment Length: 1024
• Identity: 264/1024 - (25%)
• Similarity: 392/1024 - (38%)
• Gaps: 315/1024 - (30%)

  Fly    30 PQRQQCVTVLFLDDITHTFRIEKRAKGSELLDQVFQYLELSERDYFGLLFPQKPGDVVRWVDAQK 94
            |.||..:.|..|||....|.:.:||.|..|.|.|..:|.|.|.|||||.| |....::.|:|..|
Zfish    37 PGRQISIRVQMLDDTQEVFEVSQRAPGKALFDLVCSHLNLVEGDYFGLEF-QDQRKMIVWLDLLK 100

  Fly    95 QFKKQCSSVSLDNDAVPLLEFRVKFFVSDPSRLQEEFTRYQFYLQIKRNILLGKLPCSSNTQCLL 159
            ...||     :......:|.|.||||..|.::|.||.|||.|.||||.::..|:|.|:.::..||
Zfish   101 PILKQ-----IRRPKNIILRFVVKFFPPDHTQLLEELTRYLFALQIKHDLACGRLTCNESSAALL 160

  Fly   160 ASYTVQSELGDFNALEHQPGYLSGMQLLCDQTTEAERKVGELHKLHRGQLPADAEYNYLEHAKRL 224
            .::.||||:|||:.::.:. :|...:.:.:|.|..::.:| .|:.|.||.||:::|..||.|:||
Zfish   161 VAHIVQSEIGDFDEVQCKQ-HLLNNKYIPEQDTLMDKIIG-YHRKHVGQTPAESDYQLLEIARRL 223

  Fly   225 ELYGIDLHRATDSNGKELQLGVSAVGLLVFQHSLRVNTFSWSKMVKVSFKRKDFFIQLRREPSE- 288
            |:||:.||.|.|..|..|.|.|:..|:||||...::|.|:|||:.|:|||||.|.|:||.:.::
Zfish   224 EMYGVRLHPAKDREGTRLSLAVAHSGVLVFQGHTKINAFNWSKVRKLSFKRKRFLIKLRPDLNQS 288

  Fly   289 NYDTLLGFGMSSHKHAKALWKSCVEHHSFFRL-KRPHRLSRFLNISLGSKFYYSGRTELQAVQES 352
            |....|.|.|.|....|..||.|||:|:|||| :.|....:.:..:.||.|.:||||:.|.:...
Zfish   289 NCQDTLEFMMGSRDCCKVFWKICVEYHAFFRLFEEPKPKPKPVLFTRGSSFRFSGRTQRQVIDYV 353

  Fly   353 KQRGRIHKV-FVRS-------------PSKRLLGAAGGVG--------TSGSSGGTP-------- 387
            |.. ...|| |.|.             ||::   :|.|.|        .||....:|
Zfish   354 KDT-EFKKVPFERKHSKIQSNSNLSPFPSRQ---SAEGQGEMLQRNASASGHQADSPLGRTQVTV 414

  Fly   388 ----MQQHSGSESANSHNNGKPAGAGTILTITKTSRPHDNKVTSKEADSMPRKAWEQQSDEYDIQ 448
                :|:::|  |.||..||...|                  ||.|||:..:.:..:|..|:
Zfish   415 ENPALQRYTG--SLNSQTNGCRNG------------------TSDEADARLKPSPSKQQAEH--- 456

  Fly   449 LDVGFIEQCTRRFESASPSPMPPAYSSGQHSPILLPTTIADAVGHQQPESGSDLITIRLQADEQG 513
            |..|.          ||.|...|...|.|||              :.|.:|..::
Zfish   457 LSTGL----------ASHSAKGPVSRSPQHS--------------ESPSAGQMMV---------- 487

  Fly   514 RYGFNVKGGVDLSLPVQVSKVVP--HTPADRCTPRVCEGDEVLMINGRDVHGLRHEQVVAMIRDC 576
                   .|...||.|..|   |  ..|:...:|.:.:..   .|...|...:|.::...   |.
Zfish   488 -------NGQKQSLSVGQS---PDGRQPSPLTSPLLYDAG---FIRADDEDEVRRKRFPT---DK 536

  Fly   577 RHQASGELLLTVR-----------------------PQRSAPLLLEE-EPLYQYVPESDEIGSHS 617
            .:..:.|||.|.|                       |.....|:... ||:|::         |.
Zfish   537 AYFIAKELLTTERTYLKDLEVITVSFQKAVLKDEAMPDSLRNLIFANFEPVYKF---------HE 592

  Fly   618 NLLD------------------------GDALF--TQSLLLLSDGLA--SGALLAQYELMYRKNP 654
            ..|.                        ||.:.  .|.|.|||..|.  |.:|| :.|...|.:.
Zfish   593 TFLKDVEQRLAQWEGRSNAHIKGDYQRVGDVMLKNIQGLKLLSSHLQKHSESLL-ELEQSCRSSR 656

  Fly   655 DLAIT----EARKPANAPKN-----------RYRDISPYDC------------TRVSLVN----- 687
            .|.:.    |.:|....|.|           .|:.|....|            :|.:|.:
Zfish   657 RLEVLCRDFELQKVCYLPLNIFFLRPLHRLLHYKQILERLCKHYPPTHDDFRDSRAALADVSELV 721

  Fly   688 -----------------SLTGDYINANYVNMEIPGGAVNRYIATQGPLASTTTDFWRMVQQESSH 735
                             .|..|.:..:  ::..||    |.....|.|:..:   .:.:||....
Zfish   722 LQLHTTLMKMENFQKLLELKKDLVGID--SLAAPG----REFIRLGCLSKLS---GKGLQQRMFF 777

  Fly   736 L---LVMLTT--VMESGRQKCHQYWPVTGEELQLAEGFSVRCLSEKPDETGSFVFREFVLKDKHE 795
            |   :||.|:  :..|.:.|.|...|:.|..::           |..||.|
Zfish   778 LFSDVVMYTSRGLTASNQFKVHGQLPLYGMTIR-----------ESEDEWG-------------- 817

  Fly   796 QRHIHHMQYLAWPDHCVPSDPNLFLEFTERVRAARNRTLLQEIEESLKQVRLMDADADADENGGL 860
                            ||....||.:....|.||.:.:   |:|:.::.:|:....|| ..||..
Zfish   818 ----------------VPYSFTLFGQRQSVVVAASSAS---EMEKWIEDIRMAIELAD-KSNGPT 862

  Fly   861 MRERKCAASNGATPED--------------------ETP--VSTSVHQC 887
            ......:.|:..:|||                    :||  .:|:||.|
Zfish   863 TEILSSSFSDSKSPEDCSADQESEDDLSSSRSSLERQTPHRGNTTVHVC 911

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ptpmeg	NP_001163309.2	B41	35..232	CDD:214604	75/196 (38%)
		FERM_N	38..102	CDD:286467	26/63 (41%)
		FERM_M	125..232	CDD:278785	42/106 (40%)
		FERM_C_PTPN4_PTPN3_like	226..320	CDD:270010	44/94 (47%)
		FA	333..369	CDD:285894	15/49 (31%)
		PDZ_signaling	502..589	CDD:238492	16/88 (18%)
		Y_phosphatase	666..955	CDD:278528	53/294 (18%)
		PTPc	668..955	CDD:238006	53/292 (18%)
farp1	XP_017211441.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910