Protein Alignment mth and adgrf7

DIOPT Version :10

• Sequence 1: NP_728521.1
• Gene: mth / 38058
• FlyBaseID: FBgn0023000
• Length: 522
• Species: Drosophila melanogaster
• Sequence 2: XP_073789637.1
• Gene: adgrf7 / 613165
• ZFINID: ZDB-GENE-041001-214
• Length: 704
• Species: Danio rerio
• Alignment Length: 584
• Identity: 113/584 - (19%)
• Similarity: 195/584 - (33%)
• Gaps: 176/584 - (30%)

  Fly    10 STVILVV--------LVIQKSYADILECDYFDTVDI-----------------------SAAQKL 43
            :||.::|        ::|.||   ::| |:..||||                       ||.:.:
Zfish   198 TTVEMLVNIASVSQNIIISKS---VME-DFLKTVDILVSNEATASWQSLTKENTSISLLSAVEDI 258

  Fly    44 QN----GSYL----------------FEG----------LLVPAILTGE----YDF----RILP- 69
            .|    ||:.                :.|          :|:|.||...    ..|    .|||
Zfish   259 SNRLTEGSFTINQKYIELNRTVINNSYTGKSNLPNSATEILIPQILNPTSLTIIIFTTLNNILPT 323

  Fly    70 DDSKQKVARHIRGCVCKLKPCVRFCCPHDHIMDNGVCYDNMSDEELAELDPFLNVTLDDGSVSRR 134
            .||...:          :||.:|.         ||......:::.|..:....:.|  |.|:...
Zfish   324 QDSANGI----------VKPDMRI---------NGDLVVVKANQTLHSISFVFDTT--DQSLGNP 367

  Fly   135 H--FKNELIVQWDLPMPCDGMFYLDNREEQDKYTLFENGTFFRHFDRVTLRKREYCLQHLTFADG 197
            .  |.|..:..||    ..|......|.|....|...|     |....::....:.:.|:.||..
Zfish   368 QCVFWNFNLSAWD----STGCEVKPGRNETGIITCECN-----HTASFSILMSPFSIDHIAFAYV 423

  Fly   198 NATSIRIAPHNCLIVPSITGQTVVMISSLICMVLTIAVYLFVKKLQNLHGKCFICYMVCLFMGYL 262
            ....:.|                    |:.|::|.:.:...|.|....:...::.::..:.:...
Zfish   424 TYIGVGI--------------------SVACLILCLIIEAIVWKAVRRNDTSYMRHVSIVNIAIS 468

  Fly   263 FLLLDLWQI---SIS--------FCKPAGFLGYFFVMAAFFWLSVISLHL-WNTFRGSSHKANRF 315
            .|:.|:..|   :||        .|....|..:.|.:|.|||:.:.:|.| :......|..:...
Zfish   469 LLIADVCFIIGAAISKEQPTPADRCSSVVFFMHLFYLALFFWMLISALLLFYRVVMVLSQMSRAK 533

  Fly   316 LFEHRFLAYNTYAWGMAVVLTGITVLA----DNIVENQDWNPRVGHEGHCWIYTQAWSAMLYFYG 376
            :....||    ..:|..::::.|||.:    ...|..|          .||:.......:|.|..
Zfish   534 MMVIAFL----LGYGAPLLISVITVASTAGPQMYVSKQ----------ACWLNWNESRNLLAFVI 584

  Fly   377 PMVFLIAFNITMFILTAKRILGVKKDIQNFAHRQERKQKLNSDKQTYTFFLRLFIIMGLSWSLEI 441
            |.:.::|.|:.:||:...:|.   |.....|.:.:.|..| ...:...||... :..|::|...|
Zfish   585 PALTIVAINLVVFIVVLYKIF---KRRAGAATQPDWKNAL-VVARCVAFFTPA-LACGITWGFGI 644

  Fly   442 GSYFSQSNQTWANVF--LVADYLNWSQGIIIFILFVL-------KRSTWRLLQERNHPKSTRSV 496
            |:..|      |.:|  :|....|..||..|.:...|       :.:.|..|:..|....||.:
Zfish   645 GTTVS------AGLFVHVVFALFNSLQGFFILVFGTLLDSKVREELARWFSLRNLNSSSCTRMI 702

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mth	NP_728521.1	Methuselah_N	29..209	CDD:429053	44/243 (18%)
		7tmB3_Methuselah-like	219..488	CDD:410632	59/293 (20%)
		TM helix 2	247..269	CDD:410632	2/21 (10%)
		TM helix 3	277..304	CDD:410632	8/27 (30%)
		TM helix 4	321..341	CDD:410632	5/19 (26%)
		TM helix 5	367..396	CDD:410632	7/28 (25%)
		TM helix 6	418..445	CDD:410632	6/26 (23%)
		TM helix 7	453..478	CDD:410632	8/33 (24%)
adgrf7	XP_073789637.1	None