DRSC/TRiP Functional Genomics Resources

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Protein Alignment mth and Cirl

DIOPT Version :10

Sequence 1:NP_728521.1 Gene:mth / 38058 FlyBaseID:FBgn0023000 Length:522 Species:Drosophila melanogaster
Sequence 2:XP_061501929.1 Gene:Cirl / 1278792 VectorBaseID:AGAMI1_008213 Length:1475 Species:Anopheles gambiae


Alignment Length:136 Identity:27/136 - (19%)
Similarity:45/136 - (33%) Gaps:57/136 - (41%)


- Green bases have known domain annotations that are detailed below.


  Fly   134 RHFK-----NELIVQWDLPMPCDGMFYLDNREEQD----KYTLFENGTFFRHFDRVTLRKREYCL 189
            ||.:     |...|.|:         |:|:...:|    :||   |.|            ...|:
Mosquito   892 RHLRTKNVSNPTCVFWN---------YIDHAWSEDGCHVEYT---NST------------HTVCM 932

  Fly   190 -QHLT------FADGNATSIRIAPHNCLIVPSITGQTVVMISSLICMVLTIAVYLFVKKLQNLHG 247
             .|||      .|..|.|.:.:..|        ...::::...:..:|..:.:.||.:||     
Mosquito   933 CNHLTNFALLVDAVDNETQLSLLSH--------LDDSLLLYIGIAVLVAVVVIALFARKL----- 984

  Fly   248 KCFICY 253
                ||
Mosquito   985 ----CY 986

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
mthNP_728521.1 Methuselah_N 29..209 CDD:429053 20/90 (22%)
7tmB3_Methuselah-like 219..488 CDD:410632 7/35 (20%)
TM helix 2 247..269 CDD:410632 2/7 (29%)
TM helix 3 277..304 CDD:410632
TM helix 4 321..341 CDD:410632
TM helix 5 367..396 CDD:410632
TM helix 6 418..445 CDD:410632
TM helix 7 453..478 CDD:410632
CirlXP_061501929.1 None
Blue background indicates that the domain is not in the aligned region.

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