DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment mthl10 and si:dkey-100n23.5

DIOPT Version :9

Sequence 1:	NP_788446.2	Gene:	mthl10 / 38057	FlyBaseID:	FBgn0035132	Length:	585	Species:	Drosophila melanogaster
Sequence 2:	XP_001332705.1	Gene:	si:dkey-100n23.5 / 793886	ZFINID:	ZDB-GENE-070912-347	Length:	349	Species:	Danio rerio

Alignment Length:	214	Identity:	49/214 - (22%)
Similarity:	89/214 - (41%)	Gaps:	48/214 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   255 FSI--PFMMLTIAVYLLIPELRNQHGKSLVCYLIGLSVG--YSSLCYVQLYQVDATGVTCKVFGY 315
            |||  .|.||.: ::||  ...|...:.:|   |.|:|.  :.|:.|| :.:....|..|....:
Zfish    39 FSILACFFMLCL-IWLL--RRNNSLAQKMV---INLTVAALFDSVAYV-MGESHPEGSLCNFQAW 96

  Fly   316 TAYFFFMGAYMWLSVISFDLWHNFRGTRGINRFQEKKRFLFYSLYSWGIALVFLAFTYCAQQLTN 380
            ...:|...|.:|:.:|:|:|:.|.     :...:.:...:.|.:.:||:.::.......|....
Zfish    97 WLTYFDWTALVWVCLITFNLYLNL-----VREIRTEHYRIRYHVVAWGVPVIMSTIPLMAGYYG- 155

  Fly   381 LPANLKPGIGDGVYCWL--DMSNWAAMIYFYGPILAIVVANTIMFIMTAIKIHGVQREMARII-- 441
             ||        |.:||:  |...|...|: |.|:.::::.....:              ||||
Zfish   156 -PA--------GAWCWITDDHVGWRFGIW-YIPLFSLIIVMICCY--------------ARIICV 196

  Fly   442 ASENSTKNLRT---EKDKR 457
            |:|.....|.|   |:::|
Zfish   197 ANERMRSWLGTFNPERERR 215

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mthl10	NP_788446.2	Methuselah_N	56..236	CDD:284145
mthl10	NP_788446.2	7tm_4	244..514	CDD:304433	49/214 (23%)
si:dkey-100n23.5	XP_001332705.1	7tm_4	40..193	CDD:304433	39/189 (21%)
si:dkey-100n23.5	XP_001332705.1	Git3_C	212..277	CDD:288797	1/4 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910