Protein Alignment mthl10 and mthl8

DIOPT Version :9

• Sequence 1: NP_788446.2
• Gene: mthl10 / 38057
• FlyBaseID: FBgn0035132
• Length: 585
• Species: Drosophila melanogaster
• Sequence 2: NP_001261182.1
• Gene: mthl8 / 38013
• FlyBaseID: FBgn0052475
• Length: 492
• Species: Drosophila melanogaster
• Alignment Length: 534
• Identity: 130/534 - (24%)
• Similarity: 224/534 - (41%)
• Gaps: 94/534 - (17%)

  Fly    13 YCGVTLLGVLCLVVFRLIPGIPFGTYV---MAERDHYHTIDDPNVPCNFYDTVNLTG-HRLFPNG 73
            :|   :||||.::         .||:.   ..|..||        ||.|.||.|:|| :.|  :|
  Fly     4 FC---ILGVLLIL---------SGTHCSWGFHEETHY--------PCAFIDTANITGSYGL--DG 46

  Fly    74 SYDYYGTIVPAELVGTYDY-IHSSLTERIEVREHVRGCVCKFKSCLNICCPWRQVFNSEVDGCII 137
            .:.:..|::|...|..||: |.:.:  ||....|:|.||||.|.|:.|||...::::.|...|::
  Fly    47 PFVHNWTVIPRHFVAVYDFVIENGI--RIPASRHLRACVCKTKPCVRICCLRGEIYDLEKRQCLV 109

  Fly   138 DHSDNRTWPDPPMLNITFRNESTILVNMFTQFAIQSFRPCPKMFSLQPETNNWDDYLLFENGSML 202
            ..:...:.|....:.:...|.|..||.:..:|:|....||..|.:: .:.:.:..:.|.|||:
  Fly   110 PVAGVSSLPSHSHMEVELGNGSLRLVKLQPRFSIHVETPCEHMKAV-TKGSEYVHWTLHENGT-- 171

  Fly   203 RVDDKLLIRKNEFCMVPTYVNESDMFYTIHPANCDMQDDHSTVKIIN-SYA--MMFSIPFMMLTI 264
             :..:..|....:|..|.....|.  :...|..|..:..:..:.:.. :||  ::.:|..|.:.:
  Fly   172 -ISHRGHIFSKHYCFTPLLHGNST--WEWQPLACAPEKLYFVLGVREWTYAICLLIAILSMFIVL 233

  Fly   265 AVYLLIPELRNQ-HGKSLVCYLIGLSVGYSSLCYVQLYQ-VDATGVTCKVFGYTAYFFFMGAYMW 327
            .|||:..|:||. :|.::..|.|.:.:||:.|.|:.|:. .:.:...|::....|....:.::..
  Fly   234 MVYLMCSEMRNSFYGVAIKAYAICMILGYALLAYLTLHNPANLSNAACRILPSLALMNLVLSFYI 298

  Fly   328 LSVISFDLWHNFRGTRGINRFQEKKRFLFYSLYSW----GIALV------FLAFTYCAQQLTNLP 382
            ||.|:|.|:.:|.|.            :|..|..|    .|.||      |:.|:|...:|
  Fly   299 LSFIAFKLYLSFYGV------------VFTKLMFWLIFTPIVLVAVGWSFFVGFSYYGSRL---- 347

  Fly   383 ANLKPGIGDGVYCWLDMSNWAAMIYFYGPILAIVVANTIMFIMTAIKIHGVQREMARIIASENST 447
                  |..|..||.|..||:.|||||.|:......:...::::.|.|              ...
  Fly   348 ------IFGGDTCWFDPRNWSVMIYFYAPVFVACAISGFFYVLSQIYI--------------RDQ 392

  Fly   448 KNLRTEKDKRFYRAWSNYRFGLFLRLFLIMGITWLTELISYFVGSDKGW---SKLFYISDLANAM 509
            .::.|||.   :.:....||..|.:.|....:.|:..:.|:  ..:..|   |.|.|......|.
  Fly   393 PDIETEKS---FESIEKNRFKSFWKYFGYTAVVWVVCICSF--AFNYYWENRSHLNYAVSFCMAF 452

  Fly   510 QGFLIFMLFVMKKK 523
            .||......:.|.:
  Fly   453 HGFAALYALIGKNQ 466

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mthl10	NP_788446.2	Methuselah_N	56..236	CDD:284145	49/181 (27%)
		7tm_4	244..514	CDD:304433	68/287 (24%)
mthl8	NP_001261182.1	Methuselah_N	30..202	CDD:284145	49/181 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45462219
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D111500at6656
OrthoFinder	1	1.000	-	-		FOG0003851
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR47154
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.950