Protein Alignment mthl10 and mthl13

DIOPT Version :9

• Sequence 1: NP_788446.2
• Gene: mthl10 / 38057
• FlyBaseID: FBgn0035132
• Length: 585
• Species: Drosophila melanogaster
• Sequence 2: NP_788325.2
• Gene: mthl13 / 246395
• FlyBaseID: FBgn0050018
• Length: 440
• Species: Drosophila melanogaster
• Alignment Length: 421
• Identity: 101/421 - (23%)
• Similarity: 183/421 - (43%)
• Gaps: 41/421 - (9%)

  Fly   117 CLNICCPWRQVFNSEVDGCIIDHSDNRTWPDPPMLNITFRNESTILVNMFTQ-FAIQSFRPCPKM 180
            |:.||||.:.:..:  .||.......||..|   |||...:.||..:....| ..|.||....:|
  Fly    49 CIPICCPRKNMMAN--GGCSFKEHLFRTKLD---LNIRLDDNSTEALYFNNQTLLITSFWDIDEM 108

  Fly   181 FSLQPETNNWDDYLLFENGSMLRVDDKLLIRKNEFCMVPTYVNESDMFYTIHPANCDMQDDHSTV 245
            ..|:.     |:|.|::||::....|:.:..|.|:|..|..: .||...||    ..:....|::
  Fly   109 MGLRR-----DEYTLYKNGTIYIHSDQSIQTKEEYCFYPHQI-YSDFPETI----WIISHKFSSI 163

  Fly   246 KIINSYAMMF-SIPFMMLTIAVYLLIPELRNQHGKSLVCYLIGLSVGYSSLCYVQLYQVDATGVT 309
            :...::.:.. ||...::...:||.:.||||..||.::..:..|.:.|......:|..:|.   .
  Fly   164 ESPGAFELASGSIICYIIIFGIYLFVKELRNDFGKCVMSCVFCLFLDYLIWLMDELRLLDD---F 225

  Fly   310 CKVFGYTAYFFFMGAYMWLSVISFDLWHNFRGTRGINRFQEKKRFLFYSLYSWGIALVFLAFTYC 374
            |.:.||..:||.....:|.|:||:.:|...  |..::: :.:.:|:|||.:::||:.:.|.....
  Fly   226 CSLTGYIMFFFDFANSVWFSIISYCIWKKI--TSVVSQ-ENRDQFVFYSTFAYGISAIPLGIIIS 287

  Fly   375 AQQLTNLPA---NLKPGIGDGVYCWLDMSNWAAMIYFYGPILAIVVANTIMFIMTAIKIHGVQRE 436
            ..|......   |..|.:|.. .|.:|....::.:|::.|...:...|.|||::|
  Fly   288 INQFWEEDLRKWNWLPLVGFS-RCSVDDCKRSSWVYYFVPYAIMCAINIIMFVLT---------- 341

  Fly   437 MARIIASENSTKNLRTEKDKRFYRAWSNY----RFGLFLRLFLIMGITWLTELISYFVGSDKGWS 497
            :..|:.::.:..||....|:.......|:    .:.||||:..|||:.|:..:......:...|.
  Fly   342 IKHIMKTKRNLHNLTKRPDRNETCVTVNFLNFELYLLFLRISGIMGVAWILIIFLLIEVNSTFWD 406

  Fly   498 KLFYISDLANAMQGFLIFMLFVMKKKVKHLI 528
            ....|....:...|.::|:|.:.|:....|:
  Fly   407 IFGIIIQQIHYGFGIILFVLLIFKRSTHQLL 437

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mthl10	NP_788446.2	Methuselah_N	56..236	CDD:284145	35/119 (29%)
		7tm_4	244..514	CDD:304433	61/277 (22%)
mthl13	NP_788325.2	Mth_Ecto	<49..158	CDD:299804	35/123 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45449112
Domainoid	1	1.000	49	1.000	Domainoid score	I4416
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	60	1.000	Inparanoid score	I5395
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D111500at6656
OrthoFinder	1	1.000	-	-		FOG0003851
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR47154
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	7	7.000