DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Atac3 and gabpb2

DIOPT Version :9

Sequence 1:	NP_001246531.1	Gene:	Atac3 / 38055	FlyBaseID:	FBgn0052343	Length:	583	Species:	Drosophila melanogaster
Sequence 2:	XP_017951779.1	Gene:	gabpb2 / 733936	XenbaseID:	XB-GENE-955082	Length:	392	Species:	Xenopus tropicalis

Alignment Length:	469	Identity:	130/469 - (27%)
Similarity:	205/469 - (43%)	Gaps:	109/469 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    52 VDLGKQLLQCARDSDVAGVKAALAHGAPFASDWLGMSALHFAAMNNQLEICEILLQGGINMDGKT 116
            :||||:||:.||..:...::..:.:||||.:||||.|.||.||........::|||.||:.|.:|
Frog     3 LDLGKRLLEAARCGEDNEIRLLMQNGAPFTTDWLGTSPLHLAAQYGHYSTVKVLLQAGISRDART 67

  Fly   117 KVDRTPLHLACYYGHERIVSLLLALKCSVNSRDMLRMTPLHWAVEKKHKGIVRLLLKCQADVTLV 181
            ||||||||:|...||..||.||:....:||:||||.||.||||.|..|..:|.||:|..|||...
Frog    68 KVDRTPLHMAAADGHTPIVDLLIKNGANVNARDMLEMTALHWASEHNHHDVVHLLIKSGADVNSY 132

  Fly   182 SKFGKTPIGLAVYTEQADVLAELEAARQAQASKKLHEESEQQAHKTKKETNEAVSSIMDEPEVIK 246
            :|||||||.:|:.....::|..::.|.|.:.             :|::....:|||    |:.|
Frog   133 NKFGKTPIDIALDKNNHELLVTMQEALQGKP-------------RTRRPNVISVSS----PQYI- 179

  Fly   247 TVDDKEMSVEERMDVLENMRGHANVLRNTALYILKTH----EIADMVQDNDDEDSKEMLNTALQN 307
                              :...|||        ..:|    |:..:     |...::|    :||
Frog   180 ------------------LAPVANV--------KSSHGQGAEVVTL-----DPSVQQM----VQN 209

  Fly   308 GRQLVL---SEGGRMLLHETKSGISGKQSTNGNARPSVAALRTNVNNSHPK-------------I 356
            |.|.|:   ::|.::      ..:.|:.|........:..::.....|.|.             :
Frog   210 GGQRVITIVTDGIQL------GSLQGQLSVGSLCSAPLVTIQNGAEGSLPNAHSLAVEVAEEQVV 268

  Fly   357 RMNVLKQKDLPSPAGVAKNKNIRIISLTDFKKLYGSDSTAKSL---QKIPASLASSGMVRHLPDG 418
            ...|:.:...|||..    |..|:.|:...:...|:...|:.|   |...|:|.:....:.|.:
Frog   269 EETVVVEVSPPSPPA----KKYRVTSVATEEGPEGNRVQARQLLEQQLKEANLRAREFRQQLRE- 328

  Fly   419 TKLVNMRQLQARQLKLPSLQRPQ----DLTALEESHSQNEAAVPSPLPSGHPASGSSLRG-QVGT 478
                ..::.:|.::||.||:|.|    ..|.:||    .:..:         .|...|.| :|..
Frog   329 ----KEQEAEAYRVKLESLERQQVNGDSFTVVEE----GDTII---------VSAEELAGVEVTE 376

  Fly   479 VQTIQLRPSLSAGS 492
            |:|::....:.|.|
Frog   377 VETVEQHCDIPAES 390

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Atac3	NP_001246531.1	Ank_4	58..106	CDD:290365	17/47 (36%)
		ANK repeat	58..83	CDD:293786	8/24 (33%)
		ANK	81..204	CDD:238125	61/122 (50%)
		ANK repeat	88..116	CDD:293786	11/27 (41%)
		Ank_2	90..181	CDD:289560	47/90 (52%)
		ANK repeat	118..149	CDD:293786	16/30 (53%)
		ANK repeat	151..181	CDD:293786	16/29 (55%)
		ANK repeat	184..211	CDD:293786	10/26 (38%)
gabpb2	XP_017951779.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002988
OrthoInspector	1	1.000	-	-		otm49348
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1982
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.000