Protein Alignment Atac3 and trp-4

DIOPT Version :10

• Sequence 1: NP_001246531.1
• Gene: Atac3 / 38055
• FlyBaseID: FBgn0052343
• Length: 583
• Species: Drosophila melanogaster
• Sequence 2: NP_493429.2
• Gene: trp-4 / 190574
• WormBaseID: WBGene00006616
• Length: 1924
• Species: Caenorhabditis elegans
• Alignment Length: 496
• Identity: 110/496 - (22%)
• Similarity: 182/496 - (36%)
• Gaps: 156/496 - (31%)

  Fly     1 MHSLGASKVVATLRAD--GHV-YPMENSN--LMHYEIRTEGDVQQKKGILVGPATCVDLGK-QLL 59
            :|..|....:..|..|  |.| .|..|:|  .||...|:     ..:.:|:.....:..|. |::
 Worm   820 LHFPGEDAKLVNLLIDYGGMVEMPSLNANETAMHMAARS-----GNQAVLLAMVNKIGAGAVQIV 879

  Fly    60 Q--------------CAR-DSDVAGVKAALAHGAPF-ASDWLGMSALHFAAMNNQLEICEILLQG 108
            |              ||| .|.||.:  .|.|.|.. ..|.:|.:|||.||.|..|.:..:|||.
 Worm   880 QNKQSKNGWSPLLEACARGHSGVANI--LLKHHARIDVFDEMGRTALHLAAFNGHLSLVHLLLQH 942

  Fly   109 GINMDGKTKVDRTPLHLACYYGHERIVSL----------------------------------LL 139
            ...::.|:|....|||||..:||.::|::                                  ||
 Worm   943 KAFVNSKSKTGEAPLHLAAQHGHVKVVNVLVQDHGAALEAITLDNQTALHFAAKFGQLAVSQTLL 1007

  Fly   140 ALKCSVNSRDMLRMTPLHWAVEKKHKGIVRLLLKCQAD----VTLVSKFGKTPIGLAVYTEQADV 200
            ||..:.|:||....||||.|.|.....:|:|.||.:.:    :|.:...|.|...:|.......|
 Worm  1008 ALGANPNARDDKGQTPLHLAAENDFPDVVKLFLKMRNNNRSVLTAIDHNGFTCAHIAAMKGSLAV 1072

  Fly   201 LAELEAARQAQASKKLHEESEQQAHKTKKETNEAVSSIMDEPEVIKTVDDKEMSVEERMDVLENM 265
            :.||                                .::|:|.||:.   |..::|.....:...
 Worm  1073 VREL--------------------------------MMIDKPMVIQA---KTKTLEATTLHMAAA 1102

  Fly   266 RGHANV----LRNTALYILKTHEIADMVQDNDDEDSKEM--LNTALQNGRQLVLSEGGRMLLH-- 322
            .||||:    |.|.|              :.:||:|..|  |:...:||...:|....::|..
 Worm  1103 GGHANIVKILLENGA--------------NAEDENSHGMTALHLGAKNGFISILEAFDKILWKRC 1153

  Fly   323 ETKSGISGKQ--STNGNA---RPSVAALRTNVNNSHPKIRMNVLKQ---------KDLPSPAG-- 371
            ..|:|::...  :..||:   ...:..::..|.:..|....:|.|:         ..|.:.:|
 Worm  1154 SRKTGLNALHIAAFYGNSDFVNEMLKHVQATVRSEPPIYNHHVNKEFSTEYGFTPLHLAAQSGHD 1218

  Fly   372 ----VAKNKNIRIISLTDFKKLYGSDSTAKSLQKIPASLAS 408
                :..|:.:::            |:|:.::..||..||:
 Worm  1219 SLVRMLLNQGVQV------------DATSTTMNVIPLHLAA 1247

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Atac3	NP_001246531.1	ANKYR	<58..251	CDD:440430	60/246 (24%)
		ANK repeat	58..83	CDD:293786	10/40 (25%)
		ANK repeat	88..116	CDD:293786	10/27 (37%)
		ANK repeat	118..149	CDD:293786	13/64 (20%)
		ANK repeat	151..181	CDD:293786	11/33 (33%)
		ANK repeat	184..211	CDD:293786	6/26 (23%)
trp-4	NP_493429.2	ANKYR	312..581	CDD:440430
		ANK repeat	352..383	CDD:293786
		ANK repeat	385..418	CDD:293786
		ANK repeat	424..454	CDD:293786
		ANK repeat	456..489	CDD:293786
		ANKYR	473..766	CDD:440430
		ANK repeat	491..523	CDD:293786
		ANK repeat	526..556	CDD:293786
		ANK repeat	558..590	CDD:293786
		ANK repeat	592..623	CDD:293786
		ANK repeat	625..656	CDD:293786
		ANK repeat	658..688	CDD:293786
		ANK repeat	692..726	CDD:293786
		ANK repeat	728..753	CDD:293786
		Ank_2	733..837	CDD:463710	4/16 (25%)
		ANK repeat	761..802	CDD:293786
		ANK repeat	804..842	CDD:293786	6/21 (29%)
		ANKYR	845..1130	CDD:440430	81/340 (24%)
		ANK repeat	849..884	CDD:293786	7/39 (18%)
		ANK repeat	886..917	CDD:293786	9/32 (28%)
		ANK repeat	919..950	CDD:293786	11/30 (37%)
		ANK repeat	952..982	CDD:293786	8/29 (28%)
		ANK repeat	986..1017	CDD:293786	5/30 (17%)
		ANK repeat	1092..1123	CDD:293786	9/44 (20%)
		Ank_2	1097..1234	CDD:463710	28/162 (17%)
		ANK repeat	1204..1236	CDD:293786	5/43 (12%)
		TRPV	1209..1879	CDD:454755	9/51 (18%)
		ANK repeat	1238..1270	CDD:293786	4/10 (40%)
		ANK repeat	1272..1303	CDD:293786
		ANK repeat	1305..1336	CDD:293786
		ANK repeat	1338..1366	CDD:293786