Protein Alignment Atac3 and GABPB2

DIOPT Version :10

• Sequence 1: NP_001246531.1
• Gene: Atac3 / 38055
• FlyBaseID: FBgn0052343
• Length: 583
• Species: Drosophila melanogaster
• Sequence 2: NP_001310839.1
• Gene: GABPB2 / 126626
• HGNCID: 28441
• Length: 464
• Species: Homo sapiens
• Alignment Length: 461
• Identity: 124/461 - (26%)
• Similarity: 193/461 - (41%)
• Gaps: 105/461 - (22%)

  Fly    52 VDLGKQLLQCARDSDVAGVKAALAHGAPFASDW----------------LGMSALHFAAMNNQLE 100
            |||||:||:.||......|:..:|:||||.:||                ||.|.||.||......
Human     4 VDLGKRLLEAARKGQDDEVRTLMANGAPFTTDWFSKLRVSCGYIGDNCKLGTSPLHLAAQYGHYS 68

  Fly   101 ICEILLQGGINMDGKTKVDRTPLHLACYYGHERIVSLLLALKCSVNSRDMLRMTPLHWAVEKKHK 165
            ..|:||:.|::.|.:|||||||||:|...||..||.||:.....||::|||:||.||||.|:.|:
Human    69 TAEVLLRAGVSRDARTKVDRTPLHMAAADGHAHIVELLVRNGADVNAKDMLKMTALHWATERHHR 133

  Fly   166 GIVRLLLKCQADVTLVSKFGKTPIGLAVYTEQADVLAELEAARQAQASKKLHEESEQQAHKTKKE 230
            .:|.||:|..|||...|||.|:...:|:....|::|..|:.|.|.|.:     .:.::|:.....
Human   134 DVVELLIKYGADVHAFSKFDKSAFDIALEKNNAEILVILQEAMQNQVN-----VNPERANPVTDP 193

  Fly   231 TNEAVSSIMDEPEV------IKTVDDKEMSVEERMDVLENMRGHANVLRNTA------LYILKTH 283
            .:.|...|....||      |.:.:.|..|.:.....::......:||...|      :.:..:|
Human   194 VSMAAPFIFTSGEVVNLASLISSTNTKTTSGDPHASTVQFSNSTTSVLATLAALAEASVPLSNSH 258

  Fly   284 EIADMVQDNDDEDSKEML-NTALQNGRQLVLSEGGRMLLHETKSG-----ISGKQSTNGNARPSV 342
            ...        .:::|:: ..::.:..|.|:..||:.::.....|     |.....|.|..:|.:
Human   259 RAT--------ANTEEIIEGNSVDSSIQQVMGSGGQRVITIVTDGVPLGNIQTSIPTGGIGQPFI 315

  Fly   343 AALRTNVNNSHPKIRMNVLKQKDLPSPAGVAKNKNIRIISLTDFKKLYGSDSTAKSLQKIPASLA 407
            ..::..              |:.|..|||....:.  :|...:.:||        .|.|.|....
Human   316 VTVQDG--------------QQVLTVPAGKVAEET--VIKEEEEEKL--------PLTKKPRIGE 356

  Fly   408 SSGMVRHLPDGTKLVNMRQLQARQ--------------------------LKLPSLQRPQ----D 442
            .:..|....:|    |.|:|..:|                          |||.::.|.|    |
Human   357 KTNSVEESKEG----NERELLQQQLQEANRRAQEYRHQLLKKEQEAEQYRLKLEAIARQQPNGVD 417

  Fly   443 LTALEE 448
            .|.:||
Human   418 FTMVEE 423

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Atac3	NP_001246531.1	ANKYR	<58..251	CDD:440430	77/214 (36%)
		ANK repeat	58..83	CDD:293786	10/24 (42%)
		ANK repeat	88..116	CDD:293786	10/27 (37%)
		ANK repeat	118..149	CDD:293786	16/30 (53%)
		ANK repeat	151..181	CDD:293786	16/29 (55%)
		ANK repeat	184..211	CDD:293786	8/26 (31%)
GABPB2	NP_001310839.1	ANKYR	<10..189	CDD:440430	72/183 (39%)
		ANK repeat	10..35	CDD:293786	10/24 (42%)
		ANK repeat	54..84	CDD:293786	11/29 (38%)
		ANK repeat	86..117	CDD:293786	16/30 (53%)
		ANK repeat	119..148	CDD:293786	16/28 (57%)
		ANK repeat	152..185	CDD:293786	9/37 (24%)