| Sequence 1: | NP_612024.4 | Gene: | RhoGEF3 / 38050 | FlyBaseID: | FBgn0264707 | Length: | 3519 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_079146.2 | Gene: | PREX2 / 80243 | HGNCID: | 22950 | Length: | 1606 | Species: | Homo sapiens |
| Alignment Length: | 378 | Identity: | 96/378 - (25%) |
|---|---|---|---|
| Similarity: | 174/378 - (46%) | Gaps: | 75/378 - (19%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 3027 IRRSAVRELLDTEVNYVKLLAAICDGYLPAMSK----RID-IFSPNSIRLIFSNITAIYKFQRKF 3086
Fly 3087 LEALRRGIE-----QNQVAKVFLKMHKGFLCYSTYCNAYPRA---LIELETYDRVKDARTILENC 3143
Fly 3144 R--ESQNLAELPLSAHLLAPVQRICRYPLHLNEIIKSALEKGAKEGNDTDGAKSAGKTTDYEQLD 3206
Fly 3207 VTELDIPDSQDTVNLALEAMRGITEAVNEGKRHS---ETIARHQASFQNFKGPPL-----HLHSA 3263
Fly 3264 RFFLQVDATRQKQNLWNSSYTLFLFDNQLVYCKRD--IIKRS-------HFIYKGRIFLDRCRVV 3319
Fly 3320 NVRDG----KMFGHTIKNSLRIYSESRDKWYDFSFRSANRKHRFLSTLALERQ 3368 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| RhoGEF3 | NP_612024.4 | DUF4802 | <754..>790 | CDD:292678 | |
| SH3 | 2876..2942 | CDD:214620 | |||
| RhoGEF | 3031..3235 | CDD:279015 | 56/218 (26%) | ||
| PH_Collybistin_ASEF | 3240..3373 | CDD:269931 | 35/150 (23%) | ||
| PH | <3285..3363 | CDD:278594 | 29/90 (32%) | ||
| PREX2 | NP_079146.2 | RhoGEF | 27..213 | CDD:279015 | 56/218 (26%) |
| PH_Collybistin_ASEF | 218..364 | CDD:269931 | 35/150 (23%) | ||
| PH | 248..356 | CDD:278594 | 30/113 (27%) | ||
| DEP_1_P-Rex | 382..462 | CDD:239886 | |||
| DEP_2_P-Rex | 474..566 | CDD:239887 | |||
| PDZ_signaling | 595..670 | CDD:238492 | |||
| PDZ_signaling | 677..744 | CDD:238492 | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1581..1606 | ||||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E1_KOG3519 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 1 | 1.000 | - | - | otm40937 | |
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 3 | 2.810 | |||||