| Sequence 1: | NP_612024.4 | Gene: | RhoGEF3 / 38050 | FlyBaseID: | FBgn0264707 | Length: | 3519 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | XP_016870597.1 | Gene: | VAV2 / 7410 | HGNCID: | 12658 | Length: | 896 | Species: | Homo sapiens |
| Alignment Length: | 563 | Identity: | 117/563 - (20%) |
|---|---|---|---|
| Similarity: | 197/563 - (34%) | Gaps: | 171/563 - (30%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 3028 RRSAVRELLDTEVNYVKLLAAICDGYLPAMSKRIDIFSPNSIRLIFSNITAIYKFQRKFLEALRR 3092
Fly 3093 G--IEQNQVAKVFLKMHKGFLCYSTYCNAYPRALIELETYDRV----KDARTILENCRESQNLAE 3151
Fly 3152 LPLSAHLLAPVQRICRYPLHLNEIIKSALEKGAKEGNDTDGAKSAGKTTDYEQLDVTELDIPDSQ 3216
Fly 3217 DTVNLALEAMRGITEAVNEGKRHSET---IARHQASFQNFK------GPPLHLHSARFFLQVDAT 3272
Fly 3273 RQKQNLWNSSYT---LFLFDNQLVYCKR--------------------------DIIKRSHF--- 3305
Fly 3306 ----IYKGRIFLDRCRVVNVRDGKMFGHTI-------KNSLRIYSESRD---KWYD-FSFR---- 3351
Fly 3352 ---SANRKHRFLSTLALERQFGGKAL-----------YVSEMTGFEYNYE----ERPGDYSDQSD 3398
Fly 3399 YDAQDFELATGVTSGESSL--------PESPAK-----STSRLCETLPKKSQSRDGISSAENSQI 3450
Fly 3451 VTTTSTGSLGRRHFGNWFRKPKSANCTPSQSPTHKPSFDADAT 3493 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| RhoGEF3 | NP_612024.4 | DUF4802 | <754..>790 | CDD:292678 | |
| SH3 | 2876..2942 | CDD:214620 | |||
| RhoGEF | 3031..3235 | CDD:279015 | 48/209 (23%) | ||
| PH_Collybistin_ASEF | 3240..3373 | CDD:269931 | 33/195 (17%) | ||
| PH | <3285..3363 | CDD:278594 | 23/128 (18%) | ||
| VAV2 | XP_016870597.1 | CH_VAV2 | 2..120 | CDD:409112 | |
| RhoGEF | 202..375 | CDD:214619 | 48/209 (23%) | ||
| PH_Vav | 389..534 | CDD:269930 | 27/163 (17%) | ||
| C1_VAV2 | 537..594 | CDD:410418 | 9/56 (16%) | ||
| SH3_VAV2_1 | 608..667 | CDD:212913 | 12/68 (18%) | ||
| SH2_Vav2 | 685..787 | CDD:198269 | 2/3 (67%) | ||
| SH3_VAV2_2 | 837..894 | CDD:212910 | |||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 0 | 0.000 | Not matched by this tool. | |||
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 1 | 1.030 | - | avgDist | Average_Evolutionary_Distance | R1291 |
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 2 | 1.940 | |||||