Sequence 1: | NP_612024.4 | Gene: | RhoGEF3 / 38050 | FlyBaseID: | FBgn0264707 | Length: | 3519 | Species: | Drosophila melanogaster |
---|---|---|---|---|---|---|---|---|---|
Sequence 2: | NP_005419.2 | Gene: | VAV1 / 7409 | HGNCID: | 12657 | Length: | 845 | Species: | Homo sapiens |
Alignment Length: | 581 | Identity: | 121/581 - (20%) |
---|---|---|---|
Similarity: | 203/581 - (34%) | Gaps: | 166/581 - (28%) |
- Green bases have known domain annotations that are detailed below.
Fly 2848 ESYGMGRPDLEDSDSDSVASNEEAISFYPT-TYAEVLYNFTAGGPQELGLERGMLIEILRKEVGP 2911
Fly 2912 WWFGRIKKEETNLVEDI---LGPELGWFPKEFVRIIHCPETDNFFIAHRAAADEAAAEEATARAE 2973
Fly 2974 EGSVPVPVAAFAEDTDVTVTTDQSNVTLIVIESPPTPSAPSVDFVAQPDHSTIIRRSAVRELLDT 3038
Fly 3039 EVNYVKLLAAICDGYLPAMSKRIDIFSPNSIRLIFSNITAIYKFQRKFLEALRRGIEQNQVA--- 3100
Fly 3101 KVFLKMHKGFLCYSTYCNAYPRALIELETYDRV----KDARTILENCRESQNLAELPLSAHLLAP 3161
Fly 3162 VQRICRYPLHLNEIIKSALEKGAKEGNDTDGAKSAGKTTDYEQLDVTELDIPDSQDTVNLALEAM 3226
Fly 3227 RGITEAVNEGKRHSET---IARHQASFQNFKGPPLHLHSARFFLQVDATRQKQNLWNSSYTLFLF 3288
Fly 3289 DNQLVYCKR--------DIIKRSHFIYKGRIFLDRCRVVNVRDGKMFGHTIKNSLRIYSESRDKW 3345
Fly 3346 YDFSFRSANRKHRFLSTLALERQFGGKALYVSEMTGFEYNYEERPGDYSDQSDYDAQDFEL 3406 |
Gene | Sequence | Domain | Region | External ID | Identity |
---|---|---|---|---|---|
RhoGEF3 | NP_612024.4 | DUF4802 | <754..>790 | CDD:292678 | |
SH3 | 2876..2942 | CDD:214620 | 13/69 (19%) | ||
RhoGEF | 3031..3235 | CDD:279015 | 55/210 (26%) | ||
PH_Collybistin_ASEF | 3240..3373 | CDD:269931 | 28/143 (20%) | ||
PH | <3285..3363 | CDD:278594 | 17/85 (20%) | ||
VAV1 | NP_005419.2 | CH_VAV1 | 2..121 | CDD:409111 | 9/47 (19%) |
RhoGEF | 195..371 | CDD:238091 | 55/212 (26%) | ||
PH_Vav | 385..508 | CDD:269930 | 26/156 (17%) | ||
C1_VAV1 | 510..566 | CDD:410417 | 2/11 (18%) | ||
SH3_VAV1_1 | 596..658 | CDD:212912 | |||
SH2_Vav1 | 665..767 | CDD:198268 | |||
SH3_VAV1_2 | 786..839 | CDD:212909 | |||
Blue background indicates that the domain is not in the aligned region. |
Tool | Simple Score | Weighted Score | Original Tool Information | |||
---|---|---|---|---|---|---|
BLAST Result | Score | Score Type | Cluster ID | |||
Compara | 0 | 0.000 | Not matched by this tool. | |||
Domainoid | 0 | 0.000 | Not matched by this tool. | |||
eggNOG | 0 | 0.000 | Not matched by this tool. | |||
Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
Homologene | 0 | 0.000 | Not matched by this tool. | |||
Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
Isobase | 0 | 0.000 | Not matched by this tool. | |||
OMA | 0 | 0.000 | Not matched by this tool. | |||
OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
Panther | 0 | 0.000 | Not matched by this tool. | |||
Phylome | 1 | 0.910 | - | - | ||
RoundUp | 1 | 1.030 | - | avgDist | Average_Evolutionary_Distance | R1291 |
SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
TreeFam | 0 | 0.000 | Not matched by this tool. | |||
User_Submission | 0 | 0.000 | Not matched by this tool. | |||
2 | 1.940 |