Sequence 1: | NP_612024.4 | Gene: | RhoGEF3 / 38050 | FlyBaseID: | FBgn0264707 | Length: | 3519 | Species: | Drosophila melanogaster |
---|---|---|---|---|---|---|---|---|---|
Sequence 2: | NP_001316727.1 | Gene: | PLEKHG1 / 57480 | HGNCID: | 20884 | Length: | 1444 | Species: | Homo sapiens |
Alignment Length: | 717 | Identity: | 171/717 - (23%) |
---|---|---|---|
Similarity: | 262/717 - (36%) | Gaps: | 208/717 - (29%) |
- Green bases have known domain annotations that are detailed below.
Fly 2769 VSRQDEPRAFALTNGSCGVALSKMRAIRRTNSAKASSILGPFIVKTKIAKHLNIGESDKAERKAP 2833
Fly 2834 ESLPTRSLSQPNGLESYGMGRPDLEDSDSDSVASNEEAISFYPTTYAEVLYNFTAGGPQELGLER 2898
Fly 2899 GMLIEILRKEVGPWWFGRIKKEETNLVEDILGPELGWFPKEFVRIIHCPETDNFFIAHRAAADEA 2963
Fly 2964 AAEEATARAEEGSVPVPVAAFAEDTDVTVTTDQSNVTLIVIESPPTPSAPSVDFVAQPDHSTIIR 3028
Fly 3029 RSAVRELLDTEVNYVKLLAAICDGYLPAMSKRIDI-FSPNSIRLIFSNITAIYKFQRKFLEALRR 3092
Fly 3093 GIEQNQV--AKVFLKMHKGFLCYSTYCNAYPRALIELETYDRVKDARTILENCRESQNLAE---- 3151
Fly 3152 --------LPLSAHLLAPVQRICRYPLHLNEIIKSALEKGAKEGNDTDGAKSAGKTTDYEQLDVT 3208
Fly 3209 ELDIPDSQDTVNLALEAMRGITEAVNEGKR---HSETIARHQASFQNFKGPPLHLHSARFFLQVD 3270
Fly 3271 ATRQKQNLWNSSYTLFLFDNQLVYCKRDIIKRSHFIYKGRIFLDRCRVVNV-------------R 3322
Fly 3323 DGKMFGHTIKNSLRIYSESRDK--WYDFSFR----------SANRKHRFLSTLALER-------Q 3368
Fly 3369 FGGKALYVSEMTGFEYNYEERPGDYSDQSDYDAQDFELATGV--TSGESSLPE------SPAKST 3425
Fly 3426 SR 3427 |
Gene | Sequence | Domain | Region | External ID | Identity |
---|---|---|---|---|---|
RhoGEF3 | NP_612024.4 | DUF4802 | <754..>790 | CDD:292678 | |
SH3 | 2876..2942 | CDD:214620 | 13/65 (20%) | ||
RhoGEF | 3031..3235 | CDD:279015 | 58/218 (27%) | ||
PH_Collybistin_ASEF | 3240..3373 | CDD:269931 | 36/164 (22%) | ||
PH | <3285..3363 | CDD:278594 | 23/102 (23%) | ||
PLEKHG1 | NP_001316727.1 | RhoGEF | 176..351 | CDD:279015 | 59/231 (26%) |
PH_PLEKHG1_G2_G3 | 332..477 | CDD:270063 | 39/157 (25%) | ||
PH | 381..474 | CDD:278594 | 25/105 (24%) | ||
Blue background indicates that the domain is not in the aligned region. |
Tool | Simple Score | Weighted Score | Original Tool Information | |||
---|---|---|---|---|---|---|
BLAST Result | Score | Score Type | Cluster ID | |||
Compara | 0 | 0.000 | Not matched by this tool. | |||
Domainoid | 0 | 0.000 | Not matched by this tool. | |||
eggNOG | 0 | 0.000 | Not matched by this tool. | |||
Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
Homologene | 0 | 0.000 | Not matched by this tool. | |||
Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
Isobase | 0 | 0.000 | Not matched by this tool. | |||
OMA | 0 | 0.000 | Not matched by this tool. | |||
OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
Panther | 0 | 0.000 | Not matched by this tool. | |||
Phylome | 1 | 0.910 | - | - | ||
RoundUp | 1 | 1.030 | - | avgDist | Average_Evolutionary_Distance | R1291 |
SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
TreeFam | 0 | 0.000 | Not matched by this tool. | |||
User_Submission | 0 | 0.000 | Not matched by this tool. | |||
2 | 1.940 |