DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment ttm2 and ctdspl2a

DIOPT Version :9

Sequence 1:	NP_612023.1	Gene:	ttm2 / 38049	FlyBaseID:	FBgn0035124	Length:	409	Species:	Drosophila melanogaster
Sequence 2:	NP_001071012.1	Gene:	ctdspl2a / 558181	ZFINID:	ZDB-GENE-061013-647	Length:	469	Species:	Danio rerio

Alignment Length:	198	Identity:	56/198 - (28%)
Similarity:	94/198 - (47%)	Gaps:	26/198 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   192 SRKKLLPDPLQPPYVQPPYTLVLEIKDVLVH-----------------PDWTYETGWRFKKRPGV 239
            :||..||...:.   .|.::|||::.:.|||                 .|..|:...|.  ||..
Zfish   276 TRKPALPLKTRS---TPEFSLVLDLDETLVHCSLNELEDAALTFPVLFQDVIYQVYVRL--RPFF 335

  Fly   240 DVFLKECAKYFEIVVYTAEQGVTVFPLVDALDP-NGCIMYRLVRDSTHFDGGHHVKNLDNLNRDL 303
            ..||:..::.:||:::||.:.|....|::.||| ...:.:||.|:......|:::|:|:.|.|||
Zfish   336 REFLERMSQIYEIILFTASKKVYADKLLNILDPKKQLVRHRLFREHCVCVQGNYIKDLNILGRDL 400

  Fly   304 KRVVVVDWDRNSTKFHPSNSFSIPRWSGNDNDTTLFELTSFLSVLGTSEI-DDVREVLQYYNQFS 367
            .:.|::|....:..:..||...|..|..:.||..|.:|..||..|  .|: :|||..::...:..
Zfish   401 SKTVIIDNSPQAFAYQLSNGIPIESWFVDKNDNELLKLVPFLEKL--VELNEDVRPYIRERFRLH 463

  Fly   368 DSL 370
            |.|
Zfish   464 DLL 466

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ttm2	NP_612023.1	CPDc	208..336	CDD:214729	40/145 (28%)
ctdspl2a	NP_001071012.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..42
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	73..136
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	181..209
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	231..250
		HIF-SF_euk	290..445	CDD:274055	44/156 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5190
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810