DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ttm2 and UBLCP1

DIOPT Version :9

Sequence 1:	NP_612023.1	Gene:	ttm2 / 38049	FlyBaseID:	FBgn0035124	Length:	409	Species:	Drosophila melanogaster
Sequence 2:	NP_659486.2	Gene:	UBLCP1 / 134510	HGNCID:	28110	Length:	318	Species:	Homo sapiens

Alignment Length:	235	Identity:	49/235 - (20%)
Similarity:	89/235 - (37%)	Gaps:	49/235 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   158 NEVIDEFSCLPQMQQLMWRTWKSVNRFQRFFKEPSR-KKLLPDPLQPPYVQPPYTLVLEIKDVLV 221
            ::|:::|....::.::       .||.:...|...| |:...:.|.||. :....|||::...|.
Human    93 DDVVNDFDIEDEVVEV-------ENREENLLKISRRVKEYKVEILNPPR-EGKKLLVLDVDYTLF 149

  Fly   222 HPDWTYETGWRFKKRPGVDVFLKECAKYFEIVVYTA-----------EQGVTV---FPLVDALDP 272
            ......|||... .||.:..||....:.::||:::|           |.||:.   :.:...||.
Human   150 DHRSCAETGVEL-MRPYLHEFLTSAYEDYDIVIWSATNMKWIEAKMKELGVSTNANYKITFMLDS 213

  Fly   273 NGCIMYRLVRDST-----------HFDGGHHVKN---LDNLNRDLKRVVVVDWDRNSTKFHPSNS 323
            ...|.....|...           .|...:..||   .|::.|:.     :...:|..|..|...
Human   214 AAMITVHTPRRGLIDVKPLGVIWGKFSEFYSKKNTIMFDDIGRNF-----LMNPQNGLKIRPFMK 273

  Fly   324 FSIPRWSGNDNDTTLFELTSFLSVLGTSEIDDVREVLQYY 363
            ..:.|    |.|..|.:||.:|..:  :::||..::...|
Human   274 AHLNR----DKDKELLKLTQYLKEI--AKLDDFLDLNHKY 307

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ttm2	NP_612023.1	CPDc	208..336	CDD:214729	31/155 (20%)
UBLCP1	NP_659486.2	Ubl_UBLCP1	3..77	CDD:340511
		HAD_IIID1	117..311	CDD:131299	45/204 (22%)
		Phosphatase	133..294		37/171 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5190
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900