DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ttm2 and CTDSP2

DIOPT Version :9

Sequence 1:	NP_612023.1	Gene:	ttm2 / 38049	FlyBaseID:	FBgn0035124	Length:	409	Species:	Drosophila melanogaster
Sequence 2:	XP_005268613.1	Gene:	CTDSP2 / 10106	HGNCID:	17077	Length:	277	Species:	Homo sapiens

Alignment Length:	196	Identity:	59/196 - (30%)
Similarity:	86/196 - (43%)	Gaps:	33/196 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   196 LLPDPLQPPYVQPPYTLVLEIKDVLVHPDW-----------------TYETGWRFKKRPGVDVFL 243
            |||:..:..  |....:|:::.:.|||..:                 |::.  ...|||.||.||
Human    96 LLPEVTEED--QGRICVVIDLDETLVHSSFKPINNADFIVPIEIEGTTHQV--YVLKRPYVDEFL 156

  Fly   244 KECAKYFEIVVYTAEQGVTVFPLVDALDPNGCIMYRLVRDSTHFDGGHHVKNLDNLNRDLKRVVV 308
            :...:.||.|::||.......|:.|.||..|....||.|:|..|..|.:||:|..|.|||::.::
Human   157 RRMGELFECVLFTASLAKYADPVTDLLDRCGVFRARLFRESCVFHQGCYVKDLSRLGRDLRKTLI 221

  Fly   309 VDWDRNSTKFHPSNSFSIPRWSGNDNDTTLFELTSFLSVLGTSEIDDVREVLQYYNQFSDSLSQF 373
            :|....|..|||.|:..:..|..:..||.|..|......|..:|  ||      |.    ||.|.
Human   222 LDNSPASYIFHPENAVPVQSWFDDMADTELLNLIPIFEELSGAE--DV------YT----SLGQL 274

  Fly   374 R 374
            |
Human   275 R 275

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ttm2	NP_612023.1	CPDc	208..336	CDD:214729	42/144 (29%)
CTDSP2	XP_005268613.1	HIF-SF_euk	107..266	CDD:274055	48/162 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5190
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810