DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mRpL17 and MRPL17

DIOPT Version :9

Sequence 1:	NP_001261196.1	Gene:	mRpL17 / 38046	FlyBaseID:	FBgn0035122	Length:	176	Species:	Drosophila melanogaster
Sequence 2:	NP_071344.1	Gene:	MRPL17 / 63875	HGNCID:	14053	Length:	175	Species:	Homo sapiens

Alignment Length:	149	Identity:	61/149 - (40%)
Similarity:	81/149 - (54%)	Gaps:	16/149 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 GPEGRLLKLRKTVTALVKHERIELFYNRADEARGYAELLISNAIRHGDRHQATMELADYWLLEKQ 93
            |||.|:..||..:|.||:|||||..:.|.||.|||||.||... :.||.::..|.:||:||.||.
Human    21 GPESRIHLLRNLLTGLVRHERIEAPWARVDEMRGYAEKLIDYG-KLGDTNERAMRMADFWLTEKD 84

  Fly    94 LVHKLFKVLVPRYETYNVSYTRMYKAPREYPGIYYRRS-------VLELRGNPYPSLAADHSQNR 151
            |:.|||:||.|||:.....||||.:.|        .||       |:|.:||..|.|......:.
Human    85 LIPKLFQVLAPRYKDQTGGYTRMLQIP--------NRSLDRAKMAVIEYKGNCLPPLPLPRRDSH 141

  Fly   152 NLLHNVLLDEARKEFRRQK 170
            ..|.|.||...|::.|:.:
Human   142 LTLLNQLLQGLRQDLRQSQ 160

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mRpL17	NP_001261196.1	Ribosomal_L17	37..121	CDD:279529	42/83 (51%)
MRPL17	NP_071344.1	Ribosomal_L17	28..125	CDD:395953	46/105 (44%)
MRPL17	NP_071344.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	155..175		1/6 (17%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	85	1.000	Domainoid score	I8187
eggNOG	1	0.900	-	-		E1_COG0203
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H32526
Inparanoid	1	1.050	103	1.000	Inparanoid score	I4973
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55569
OrthoDB	1	1.010	-	-		D1540433at2759
OrthoFinder	1	1.000	-	-		FOG0003177
OrthoInspector	1	1.000	-	-		oto88420
orthoMCL	1	0.900	-	-		OOG6_100929
Panther	1	1.100	-	-	LDO	PTHR14413
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1152
SonicParanoid	1	1.000	-	-		X5446
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	16	15.870