DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Tudor-SN and LCL3

DIOPT Version :9

Sequence 1:	NP_001261195.1	Gene:	Tudor-SN / 38045	FlyBaseID:	FBgn0035121	Length:	926	Species:	Drosophila melanogaster
Sequence 2:	NP_011430.1	Gene:	LCL3 / 852795	SGDID:	S000003053	Length:	274	Species:	Saccharomyces cerevisiae

Alignment Length:	151	Identity:	46/151 - (30%)
Similarity:	70/151 - (46%)	Gaps:	22/151 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   545 ASGSRLRIFVP----KDSCLVTFLLAGISCPRSSRPALNGVPAQEGEPFGDEALTFTRERVLQRD 605
            |....|::.||    |:...:...|.||..|..   |..|.|||   |||:|||.:.:.|:|.:.
Yeast   128 AKSQFLKLNVPYKNRKNLPTIPIRLCGIDAPER---AHFGNPAQ---PFGNEALIWLQNRILGKK 186

  Fly   606 VSV---HIDTTDKAGSSVIGWLWTDSGANLSVALVEEGLAEVHFSAEKSEY------YRQLKIAE 661
            |.|   .||..::..:.|..|.|.....:||:.::::|||.|:.....:|:      ||..   |
Yeast   187 VWVKPLSIDQYNRCVARVSYWDWFGGWKDLSLEMLKDGLAVVYEGKVNTEFDDREDKYRYY---E 248

  Fly   662 DRAKAAKKNIWTNYVEEVPKE 682
            ..|::.||.:|.....|.|.|
Yeast   249 FLARSRKKGLWIQNKFETPGE 269

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tudor-SN	NP_001261195.1	SNc	23..166	CDD:214615
		SNc	195..333	CDD:214615
		SNc	346..504	CDD:320778
		SNc	538..672	CDD:214615	42/139 (30%)
		TUDOR	697..817	CDD:306940
		SNc	767..914	CDD:320778
LCL3	NP_011430.1	SNase	149..261	CDD:395448	38/120 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	46	1.000	Domainoid score	I3077
eggNOG	1	0.900	-	-		E1_COG1525
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		oto100269
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1361
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.840