Protein Alignment Tudor-SN and tud

DIOPT Version :10

• Sequence 1: NP_612021.1
• Gene: Tudor-SN / 38045
• FlyBaseID: FBgn0035121
• Length: 926
• Species: Drosophila melanogaster
• Sequence 2: NP_476773.1
• Gene: tud / 37417
• FlyBaseID: FBgn0003891
• Length: 2515
• Species: Drosophila melanogaster
• Alignment Length: 1026
• Identity: 198/1026 - (19%)
• Similarity: 361/1026 - (35%)
• Gaps: 287/1026 - (27%)

  Fly    19 PAPTKSLSGIVKQVLSGDTVVIRATKGAPPPEKQITFSHVLAPKLARRPGAGGDETKDEPWA-WE 82
            |:....|...:.::|....|.|::.        ::..||::|..:.....:..|..|.|... .:
  Fly  1429 PSNDTKLKARISEILEEKVVTIKSI--------EVRRSHLIADVILENNQSVIDLLKAEKLVPGK 1485

  Fly    83 SREFLRKKLIGVEVTFTFDKPANSNREY-GFVWIGKDKETGENVVESIVREGLVSVRREGRPTAE 146
            ..:::||::         :|..:...|| ..|.:..|:|..:...|::.:.|..:    ..|..:
  Fly  1486 DLDYMRKQM---------EKGKSRTYEYIETVDLTLDEEEDKGRKETVSKSGSAN----ASPKKK 1537

  Fly   147 QQTLIELEDQARAAGRGK-WSPTASAADKVRNIKWSHENPAHLVDI-YGGNPVKAIIEHVRDGST 209
            |.     .|:.|...:.| ..|..:.|.:...:|.....||....: ....||..::|......|
  Fly  1538 QH-----NDKDREPKKSKPAEPARTVAPQPVALKTPSPVPAEPAPVPKPATPVPEVVEVPEINPT 1597

  Fly   210 VRAFLLPDFHYITLMISGIRCPGVKLDADGKPDLSVKVPFAD-----------EARYYVE----- 258
            ||                      :..|:.|...:.:.|:.|           .|::||.
  Fly  1598 VR----------------------EAAAESKQAPAQEDPYKDLDCVVLSHCDNPAQFYVHPIDQL 1640

  Fly   259 TRLLQRDVEIRLES---------VNNSNFIGTILYPK--------------------GN------ 288
            ::|.|....:::.|         ||.::.:......|                    ||
  Fly  1641 SKLNQLHENLQIVSPSLPQLMNVVNGADCVSMYSVDKCWYRAKIIDAELMVLLFIDYGNTDCVSD 1705

  Fly   289 ---IAESLLREGLAKCVDWSMAVMKTGT-DKLRAA-----ERFAKEKRLRQWQDYQAKTPAFNSK 344
               |.||:.......|:..::.:...|| |.:.||     |.::|..||.........|.::.:.
  Fly  1706 ATDIKESMWSHIEPFCLPCALPIRPKGTADWVDAANGIFNESYSKVPRLEYLTQGDHYTTSYVNM 1770

  Fly   345 EKD------------FSGTVVEVFNGDAINVRLSNGQVKKVFFSSIRPPRDQRAVVGTDGEEIVK 397
            ..|            |:..:..:.:|.:..:...||...  ||  |:..||.:|:      |:::
  Fly  1771 YIDGEDVAKKLIADGFARPLEYLASGCSCYISHVNGICD--FF--IQLERDSKAL------ELIE 1825

  Fly   398 APPRGKN-YRPL--YE----IPHMFDAREF-----LRKKLINKKVQ-CNLDY-----------IS 438
            ...|.|: .:||  :|    :..:|:..|.     |:|:|.:.:.: ..:||           :|
  Fly  1826 LYLRKKDTLKPLEGFEKGLIVAALFEDDELWYRAQLQKELPDSRYEVLFIDYGNTSTTSKCLMLS 1890

  Fly   439 PPRENFP--EKYCY----TVSIGGQNVAEAMVAKGLATCVRYRQDDDQRSSAYDQLIAAEQQAIK 497
            ....:.|  .|.|.    ...|.....|||..|:                      :..|.:.:.
  Fly  1891 EEIASLPSLSKKCSLQLPDAYISWSPEAEAKFAE----------------------LTGEGELVF 1933

  Fly   498 GLKGLHAKKDNATLRVNDLTVDHSRIKVQYLPSWQR-----------ALRTEAIVEFVASGSRLR 551
            ..:.|...:|:.|:   ||.:|...|..:.||..||           |:.|:||:..|.:.||:.
  Fly  1934 TTQLLKPGQDHVTI---DLLLDGENIIDRLLPLCQRKEPKEASKESLAVTTKAIITHVENTSRIY 1995

  Fly   552 I-FVPKDSCLVTFLLAGISC---------PRSSRPALNGVPAQEGEPFGDEALTFTRERVLQ--R 604
            : |..|||      |..|.|         |::.:.|::.:...:   |.|: |.|.|.|:|:  .
  Fly  1996 LQFSEKDS------LMDIICEKLNGSKLQPKTEKAAVDDMCVVQ---FADD-LEFYRSRILEVLE 2050

  Fly   605 DVSVHIDTTDKAGSSVIGWLWTDSGANLSVALVEE-----GLAEVHFSAEKSEYYRQLKIAE--- 661
            |....:...|...::|:..|:         .|.:|     .:||: .|.|.|..:.:.|...
  Fly  2051 DDQYKVILIDYGNTTVVDKLY---------ELPQEFTLIKPVAEI-CSMEPSAIFEKNKALTLTT 2105

  Fly   662 -----DRAKAAKKNIWTNYVEEVPKEKTVTEEEK--------------EDKVVAERKVNYENVIV 707
                 |..|......:.|.....|..:..|::::              |.|::.:|..|.| .|:
  Fly  2106 FDALLDSCKGVVAVEFVNKSASPPVVRLTTKDKRSLKIYEHLQKLVQAELKLIQKRNENSE-CII 2169

  Fly   708 TEITETLTFFAQSVESGSKLESLMSKLHA-DFQSNPPIAGSYTPKRGDLVAAQFTLDNQWYRAKV 771
            :......:|:.|...:.:.|:.::..|.: ..:....:....|...|...:.:   |..:||..:
  Fly  2170 SYGNSPKSFYVQMKHNSADLDLIVKTLQSLKKEKLKKLIDPTTNSNGVCYSQE---DACYYRCSI 2231

  Fly   772 ERV----QGSNATVLYIDYGNKETLPTNRLAALPPAFSSEKPYATEYALALVALPTDNEDKEEAL 832
            :.|    ||..  |..:||||  ||....:..||.........|....|:.:.:...:|..|||.
  Fly  2232 KSVLDPSQGFE--VFLLDYGN--TLVVPEVWQLPQEIEPIPSLALHCQLSKIPMDVSDEKLEEAF 2292

  Fly   833 RAFSEDVLNHKVQLNVELKVTGSPN-------LATLRDPTTKVDFGKQLVA 876
            .|..|   .|..:|   .::|..||       :|.||  ....||.::||:
  Fly  2293 AALLE---QHFGEL---YEITTQPNEDETKPLIAELR--INYKDFVQELVS 2335

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tudor-SN	NP_612021.1	SNc	23..166	CDD:214615	25/145 (17%)
		SNc	195..333	CDD:214615	34/197 (17%)
		SNc	346..504	CDD:469627	35/199 (18%)
		SNc	538..672	CDD:214615	35/158 (22%)
		Tudor_TDRD11	723..805	CDD:410504	19/86 (22%)
		YncB	<868..926	CDD:441134	4/9 (44%)
tud	NP_476773.1	TUDOR	411..524	CDD:425754
		TUDOR	595..707	CDD:425754
		TUDOR	1016..1132	CDD:425754
		TUDOR	1309..1425	CDD:425754
		TUDOR	1620..1727	CDD:425754	15/106 (14%)
		TUDOR	1795..1906	CDD:425754	26/120 (22%)
		TUDOR	1980..2089	CDD:425754	30/128 (23%)
		TUDOR	2163..2277	CDD:425754	25/121 (21%)
		TUDOR	2347..2458	CDD:425754