DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment pyx and YAR1

DIOPT Version :9

Sequence 1:	NP_612015.1	Gene:	pyx / 38037	FlyBaseID:	FBgn0035113	Length:	956	Species:	Drosophila melanogaster
Sequence 2:	NP_015085.1	Gene:	YAR1 / 855837	SGDID:	S000006160	Length:	200	Species:	Saccharomyces cerevisiae

Alignment Length:	147	Identity:	37/147 - (25%)
Similarity:	54/147 - (36%)	Gaps:	45/147 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   264 EGKVTALHLAAENDYVECARLLLEHRAEVDCRNASHQTPLHLACLSQSIGTVDLLISYGANVNAV 328
            |...||||:||.|.::|..|.:||                   .:|::....||    .|.||.|
Yeast    48 ESDSTALHMAAANGHIETVRYILE-------------------TVSRANSAEDL----KAFVNEV 89

  Fly   329 YRDGRTALHAAIVKQSRSLDCCNALLKAGADVNKADNYGYTPLHIAALNEFSSCVYTFIEHGADI 393
            .:.|.||||.|.:  :..||....|         .|.|...|.   ..|:|.        |.|..
Yeast    90 NKTGNTALHWASL--NGKLDVVKLL---------CDEYEADPF---IRNKFG--------HDAIF 132

  Fly   394 TARTDGRVSALSFIVRR 410
            .|...|:....::.:::
Yeast   133 EAENSGKEEVETYFLKK 149

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
pyx	NP_612015.1	Ank_4	99..153	CDD:290365
		ANK repeat	102..130	CDD:293786
		ANK	127..252	CDD:238125
		ANK repeat	132..163	CDD:293786
		Ank_2	137..226	CDD:289560
		ANK repeat	166..196	CDD:293786
		ANK	198..319	CDD:238125	15/54 (28%)
		ANK repeat	200..229	CDD:293786
		Ank_2	203..296	CDD:289560	12/31 (39%)
		ANK repeat	231..262	CDD:293786
		ANK	268..387	CDD:238125	32/118 (27%)
		ANK repeat	268..296	CDD:293786	11/27 (41%)
		Ank_2	270..364	CDD:289560	25/93 (27%)
		ANK repeat	298..329	CDD:293786	6/30 (20%)
		ANK repeat	331..364	CDD:293786	9/32 (28%)
		Ank_5	353..404	CDD:290568	10/50 (20%)
		ANK repeat	366..396	CDD:293786	6/29 (21%)
		Ion_trans	556..734	CDD:278921
YAR1	NP_015085.1	ANK repeat	11..47	CDD:293786
		Ank_2	20..124	CDD:403870	31/112 (28%)
		ANK repeat	49..90	CDD:293786	17/63 (27%)
		ANK repeat	92..124	CDD:293786	12/45 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2336
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.030