DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment pyx and Asb11

DIOPT Version :9

Sequence 1:NP_612015.1 Gene:pyx / 38037 FlyBaseID:FBgn0035113 Length:956 Species:Drosophila melanogaster
Sequence 2:NP_001300666.1 Gene:Asb11 / 68854 MGIID:1916104 Length:323 Species:Mus musculus


Alignment Length:219 Identity:69/219 - (31%)
Similarity:105/219 - (47%) Gaps:19/219 - (8%)


- Green bases have known domain annotations that are detailed below.


  Fly   134 RTPLHFACCRANAPIAKVLLDFGADPNRWDARKEVTSLHCAASSKSVECILLLLRRKASINI-GI 197
            |:|||.|..:......|.|:..|.:.|.....: |:|||.|.....|.|...||...|.:|. .:
Mouse    66 RSPLHEAAAQGRLLALKTLIAQGINVNLVTINR-VSSLHEACLGGHVACAKALLENGAHVNAQTV 129

  Fly   198 EKRSALHYAIDVNAVDCVEILLKYGADPNTPQVYTETPLHTASAAGFAKCVQLLLSHNADVRS-- 260
            ...:.|..|....:..||.:||::||.... ::|..:|:|.|...|..:|:::||:.:.::..  
Mouse   130 HGATPLFNACCSGSAACVNVLLEFGAKAQL-EIYLASPIHEAVKRGHRECMEILLTKDVNIEQEV 193

  Fly   261 -QFGEGKVTALHLAAENDYVECARLLLEHRAEVDCRNASH----QTPLHLACLSQSIGTVDLLIS 320
             |.|    |.|::|.....|:|.:.|||..|.||     |    .||||.|....|:..::||..
Mouse   194 PQLG----TPLYVACTYQRVDCVKKLLELGASVD-----HGQWLDTPLHAAVRQSSVEVINLLTV 249

  Fly   321 YGANVNAVYRDGRTALHAAIVKQS 344
            ||||:|.....|::||..|:.|.|
Mouse   250 YGANLNLRNAQGKSALDLAVPKSS 273

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
pyxNP_612015.1 Ank_4 99..153 CDD:290365 6/18 (33%)
ANK repeat 102..130 CDD:293786
ANK 127..252 CDD:238125 34/118 (29%)
ANK repeat 132..163 CDD:293786 9/28 (32%)
Ank_2 137..226 CDD:289560 26/89 (29%)
ANK repeat 166..196 CDD:293786 11/30 (37%)
ANK 198..319 CDD:238125 37/127 (29%)
ANK repeat 200..229 CDD:293786 8/28 (29%)
Ank_2 203..296 CDD:289560 29/95 (31%)
ANK repeat 231..262 CDD:293786 8/33 (24%)
ANK 268..387 CDD:238125 31/81 (38%)
ANK repeat 268..296 CDD:293786 11/27 (41%)
Ank_2 270..364 CDD:289560 30/79 (38%)
ANK repeat 298..329 CDD:293786 14/34 (41%)
ANK repeat 331..364 CDD:293786 6/14 (43%)
Ank_5 353..404 CDD:290568
ANK repeat 366..396 CDD:293786
Ion_trans 556..734 CDD:278921
Asb11NP_001300666.1 ANK 1 64..93 8/26 (31%)
ANK 66..183 CDD:238125 34/118 (29%)
Ank_4 66..118 CDD:290365 16/52 (31%)
ANK repeat 66..95 CDD:293786 9/28 (32%)
ANK repeat 97..128 CDD:293786 11/31 (35%)
ANK 2 97..126 10/29 (34%)
Ank_2 102..189 CDD:289560 25/87 (29%)
ANK 3 130..159 8/28 (29%)
ANK repeat 130..155 CDD:293786 6/24 (25%)
ANK 4 162..191 8/28 (29%)
ANK 165..269 CDD:238125 37/112 (33%)
ANK repeat 165..193 CDD:293786 7/27 (26%)
Ank_2 167..258 CDD:289560 33/99 (33%)
ANK repeat 195..225 CDD:293786 13/38 (34%)
ANK 5 195..224 13/37 (35%)
ANK repeat 227..258 CDD:293786 13/30 (43%)
ANK 6 227..256 12/28 (43%)
ANK 7 260..289 6/14 (43%)
SOCS 282..323 CDD:295349
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
11.000

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