DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment pyx and Asb12

DIOPT Version :9

Sequence 1:	NP_612015.1	Gene:	pyx / 38037	FlyBaseID:	FBgn0035113	Length:	956	Species:	Drosophila melanogaster
Sequence 2:	NP_001032444.1	Gene:	Asb12 / 503446	RGDID:	1561142	Length:	308	Species:	Rattus norvegicus

Alignment Length:	185	Identity:	56/185 - (30%)
Similarity:	88/185 - (47%)	Gaps:	37/185 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   169 TSLHCAASSKSVECILLLLRRKASI-NIGIEKRSALHYAIDVNAVDCVEILLKYGADPNTPQVYT 232
            |.|..|||...::|:.:||...|.: ::.::.::.|..|:....::||.|||:.||.| :..:|.
  Rat    66 TPLRLAASYGHLDCVKVLLEHGADVDSLDVKAQTPLFTAVSHGHLECVRILLEAGACP-SGSIYN 129

  Fly   233 E-TPLHTASAAGFAKCVQLLLSHNADVRSQFGEGKVTA---------------LHLAAENDYVEC 281
            . :|:.|||..|....:|.||.|.|       |..|.|               |:|||...:::|
  Rat   130 NCSPVLTASRDGAFAILQELLGHGA-------EANVKAKLPVWASNIASCSGPLYLAAVYGHLDC 187

  Fly   282 ARLLLEHRAEVD--C-------RNASHQTPLHLACLSQSIGT--VDLLISYGANV 325
            .||||.:.|:.|  |       |....:|.|.: ||..:...  :.|||.:|||:
  Rat   188 FRLLLLYGADPDYNCIDQALLSRVPQPRTLLEI-CLHHNCEPEYIQLLIDFGANI 241

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
pyx	NP_612015.1	Ank_4	99..153	CDD:290365
		ANK repeat	102..130	CDD:293786
		ANK	127..252	CDD:238125	26/84 (31%)
		ANK repeat	132..163	CDD:293786
		Ank_2	137..226	CDD:289560	18/57 (32%)
		ANK repeat	166..196	CDD:293786	9/27 (33%)
		ANK	198..319	CDD:238125	42/147 (29%)
		ANK repeat	200..229	CDD:293786	10/28 (36%)
		Ank_2	203..296	CDD:289560	36/117 (31%)
		ANK repeat	231..262	CDD:293786	11/31 (35%)
		ANK	268..387	CDD:238125	24/84 (29%)
		ANK repeat	268..296	CDD:293786	13/51 (25%)
		Ank_2	270..364	CDD:289560	23/67 (34%)
		ANK repeat	298..329	CDD:293786	10/30 (33%)
		ANK repeat	331..364	CDD:293786
		Ank_5	353..404	CDD:290568
		ANK repeat	366..396	CDD:293786
		Ion_trans	556..734	CDD:278921
Asb12	NP_001032444.1	ANK repeat	66..94	CDD:293786	9/27 (33%)
		Ank_2	68..159	CDD:403870	30/98 (31%)
		ANK repeat	96..160	CDD:293786	23/71 (32%)
		ANK repeat	173..199	CDD:293786	10/25 (40%)
		Ank	175..199	CDD:394980	10/23 (43%)
		SOCS_box	268..306	CDD:400074
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000