Protein Alignment pyx and LOC4577455

DIOPT Version :10

• Sequence 1: NP_612015.1
• Gene: pyx / 38037
• FlyBaseID: FBgn0035113
• Length: 956
• Species: Drosophila melanogaster
• Sequence 2: XP_001238502.3
• Gene: LOC4577455 / 4577455
• VectorBaseID: AGAMI1_005230
• Length: 809
• Species: Anopheles gambiae
• Alignment Length: 780
• Identity: 162/780 - (20%)
• Similarity: 291/780 - (37%)
• Gaps: 238/780 - (30%)

  Fly   153 LDFGADPNRWDARKEVTSLHCAASSKSV-ECILLLLRRKASIN-IGIEKRSALHYAIDVNA---- 211
            |..||..|:...|.|. .:|.||.|:.: ..:|||||.:.::| :..:..||:.:....:|
Mosquito    67 LAHGARVNKKSGRGEY-PIHQAAKSRDINNLMLLLLRHEVNVNQLSDDGNSAIDFICPSHAHTFA 130

  Fly   212 --VDCVEILLKYGADPNTPQVYTETPLHTASAAGFAKCVQLLLSHNADVRSQFGEG-----KVTA 269
              ::|:.:|||:||              |...|..||.: ..|....::.::|.:|     .|||
Mosquito   131 KSIECINLLLKHGA--------------TIDTANLAKRL-AKLKQETEILAEFMQGIEPFVTVTA 180

  Fly   270 LHL-AAENDYVECARLLLEHRAEVDCRN--------ASHQTPLHLACLSQSIGTVDL------LI 319
            ..| ..|.:.|: ..:|||:  .:.|.|        .||.:|.....:|:.|.|:..      ::
Mosquito   181 TGLPETETETVD-NHMLLEN--AITCGNLERAKQIIESHASPQTSPYISKKILTICFERGCFEML 242

  Fly   320 SY----------------------------GANVNAVY-----------------RDG--RTALH 337
            .|                            |::....:                 |||  .||||
Mosquito   243 EYIFQILPAAGIESRITKKTWLSFLVQRVTGSDPECRFFKCLKLCLTYPQFDIDERDGWDYTALH 307

  Fly   338 AAIVKQSRSLDCCNALLKAGADVNKADNYG-YTPLHIAAL---NEFSSCVYT----FIEHGADIT 394
            .|...:.:.|.  ..||:.||.:...|.:| ||...|..|   ..|.|||||    ..||||:
Mosquito   308 YAATLKLKHLQ--ELLLQKGAYIGGRDIFGVYTISQIDPLVLVRHFDSCVYTSPRIADEHGAN-- 368

  Fly   395 ARTDGRVSALSFIVRRTPEIIPKLMQKLDSSIKANDQEIGDVDCQIK------LDFRLLVPSSSM 453
                   |.:.:::..  ...|...::.::|.|:.    .:||...|      ::|..:...|.:
Mosquito   369 -------SPIVYVMLN--NFAPPKHEENNASPKSK----SNVDVSYKSMRPALMEFTNVSKLSRL 420

  Fly   454 DRGETELLLSLIEVGQKRILMHPLCETFLF------------LKWRRIRKFFLMSLAYHT----- 501
            :..|.:        .::::|.||:..|||:            |::.|:....|:.:.:.:
Mosquito   421 NEKEKK--------ARQQLLEHPVIATFLYIREPPPTTVGLLLRFIRLVPAILLFVPWDSRWFIW 477

  Fly   502 ----LFVILFTFYVIW--VYV------RCCKKEELCVAPGYVSTIGYLVIILNLILLGKEVFQMA 554
                |.:.||.|.||.  .|:      |...|.:....|..:.|:...::::..::
Mosquito   478 CESVLLICLFIFEVILNASYITHFFDKRIKNKFQSVPNPTILFTMLVEIVLIACLI--------- 533

  Fly   555 HGLRGYAKYWENWLQWTIGTGVLLC--VTPETVRTDDLTAVPVWQHHVAAIVILLVWLELMMLVG 617
                 |..:.|....:.:...:||.  .|...:.:.|..|..:   |...||:..|...  .::.
Mosquito   534 -----YFTFLEYSKVYQLRCCILLAGFATKRFIASWDCLAEKI---HTLDIVVTKVICN--FIIC 588

  Fly   618 RFPIFGVYVQMFTKVAVNFAKFLLAYICLLVAFGLSFAVLFNDYPAFENI--TWSFLKSITMMSG 680
            .| |||::|..|.....||.:          .|..|.....:.....|:|  |...:..:.|..|
Mosquito   589 SF-IFGIFVLSFCVHDSNFGQ----------TFVPSNNTASSTNTTIESISKTAKLIDQLAMFDG 642

  Fly   681 EL-----EFEDIFYGDYAVKFPVTAHIIFLSFVLLVTVILTNLMVGLAVSDIQGLQVSATLDRLV 740
            ::     :.:..|||           :.|:||::|:.:.|.|::..||::|:..|...:
Mosquito   643 KIIVLDKKMDLAFYG-----------VGFVSFLILMPIALANIITALAITDVSELTARS------ 690

  Fly   741 RQAELVSRLESLFFS-----RLLRSAPTNLIQLCKRSALL--------------RTSRDKLQFTI 786
            |..::..|:.:.|..     .|.|.. :..::...||:||              .:|:.||.|::
Mosquito   691 RCVKIALRISNAFVPEHPAVELWRGM-SKYMEEQSRSSLLSWWRSNRAVNTISSNSSKAKLCFSL 754

  Fly   787  786
            Mosquito   755  754

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pyx	NP_612015.1	Ank_2	88..161	CDD:463710	3/7 (43%)
		ANK repeat	102..130	CDD:293786
		ANK repeat	132..163	CDD:293786	4/9 (44%)
		ANKYR	148..435	CDD:440430	84/364 (23%)
		ANK repeat	166..196	CDD:293786	11/31 (35%)
		ANK repeat	200..229	CDD:293786	9/34 (26%)
		ANK repeat	231..262	CDD:293786	5/30 (17%)
		ANK repeat	268..296	CDD:293786	9/28 (32%)
		ANK repeat	298..329	CDD:293786	8/64 (13%)
		ANK repeat	331..364	CDD:293786	12/34 (35%)
		ANK repeat	366..396	CDD:293786	15/37 (41%)
		Ion_trans	<562..734	CDD:459842	38/180 (21%)
LOC4577455	XP_001238502.3	None