DRSC/TRiP Functional Genomics Resources

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Protein Alignment pyx and Sowahc

DIOPT Version :9

Sequence 1:NP_612015.1 Gene:pyx / 38037 FlyBaseID:FBgn0035113 Length:956 Species:Drosophila melanogaster
Sequence 2:NP_766527.3 Gene:Sowahc / 268301 MGIID:3606051 Length:512 Species:Mus musculus


Alignment Length:246 Identity:61/246 - (24%)
Similarity:99/246 - (40%) Gaps:54/246 - (21%)


- Green bases have known domain annotations that are detailed below.


  Fly   240 SAAGFAKCVQLLLSHNADVRSQFGEGKVTALHLAAENDYVECARLLL----EHR--AEVDCRNAS 298
            |..|...|...|||     :..|..| .|.||.||::...|...:|:    :|:  ..::.:::.
Mouse   269 SLEGLLTCEPGLLS-----KRDFITG-FTCLHWAAKHGRQELLAMLVNFATKHQLPVNINAKSSG 327

  Fly   299 HQTPLHLACLSQSIGTVDLLI-SYGANVNAVYRDGRTA---LHAAIVKQSRSLDCCNALLKAGAD 359
            ..|.||||.:...:..|.||: :|.|:|:.....||.|   |..:|.::.::|  ..||.:...|
Mouse   328 GYTALHLAAMHGHVEVVKLLVGAYDADVDIRDYSGRKASQYLSESIAEEIKNL--VGALDEDDGD 390

  Fly   360 VNKADNYG------YTPLHIAALNEFSSCVYTFIEHGADITARTDGRVSALSFIVRRTPEIIPKL 418
            ...|...|      ..|.||.  ::.|..|    |.||::.              ...||.....
Mouse   391 SPAARGGGRWRLSKVLPSHIT--HKLSPVV----EDGAELH--------------HHVPEGWTGG 435

  Fly   419 MQKLDSSIKANDQEIGDVDCQI-KLDFRLLV----PS-----SSMDRGETE 459
            .:..||..||:....|.:..:: |:.||..:    ||     .:::.||.|
Mouse   436 SKAKDSGRKASGSSSGRMKPRLNKIRFRTQIIHTTPSFRDAKPTLEEGEEE 486

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
pyxNP_612015.1 Ank_4 99..153 CDD:290365
ANK repeat 102..130 CDD:293786
ANK 127..252 CDD:238125 3/11 (27%)
ANK repeat 132..163 CDD:293786
Ank_2 137..226 CDD:289560
ANK repeat 166..196 CDD:293786
ANK 198..319 CDD:238125 23/84 (27%)
ANK repeat 200..229 CDD:293786
Ank_2 203..296 CDD:289560 16/61 (26%)
ANK repeat 231..262 CDD:293786 6/21 (29%)
ANK 268..387 CDD:238125 35/134 (26%)
ANK repeat 268..296 CDD:293786 8/33 (24%)
Ank_2 270..364 CDD:289560 27/103 (26%)
ANK repeat 298..329 CDD:293786 11/31 (35%)
ANK repeat 331..364 CDD:293786 9/35 (26%)
Ank_5 353..404 CDD:290568 12/56 (21%)
ANK repeat 366..396 CDD:293786 9/35 (26%)
Ion_trans 556..734 CDD:278921
SowahcNP_766527.3 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 126..248
Ank_2 259..359 CDD:289560 27/95 (28%)
ANK 288..397 CDD:238125 30/111 (27%)
ANK 1 288..317 9/29 (31%)
ANK repeat 289..325 CDD:293786 9/36 (25%)
ANK repeat 327..359 CDD:293786 11/31 (35%)
ANK 2 327..357 11/29 (38%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 427..500 15/60 (25%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R2336
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
11.030

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