DRSC/TRiP Functional Genomics Resources

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Protein Alignment pyx and Ankrd35

DIOPT Version :9

Sequence 1:NP_612015.1 Gene:pyx / 38037 FlyBaseID:FBgn0035113 Length:956 Species:Drosophila melanogaster
Sequence 2:NP_001074608.1 Gene:Ankrd35 / 213121 MGIID:2442590 Length:996 Species:Mus musculus


Alignment Length:290 Identity:77/290 - (26%)
Similarity:124/290 - (42%) Gaps:61/290 - (21%)


- Green bases have known domain annotations that are detailed below.


  Fly   139 FACCRANAPIAKVLLDFGADPNRWDARKEVTSLHCAASSKSVECILLLLRRKASINIGIEKRSAL 203
            |:|..:...:.|           |:.|.:  .|..|.....|..:..|..||          ||.
Mouse     5 FSCSSSQVAVEK-----------WNRRDQ--KLLEAVQRGDVGRVAALASRK----------SAR 46

  Fly   204 HYAIDVNAVDCVEILLKYGADPNTPQVYTETPLHTASAAGFAKCVQLLLSHNADVRSQFGEGKVT 268
            ...:|.|.                     ::|.|.|::.|..:|:.:||::.||:.|:..:|. |
Mouse    47 PTKLDSNG---------------------QSPFHLAASKGLTECLTILLANGADINSKNEDGS-T 89

  Fly   269 ALHLAAENDYVECARLLLEHRAEVDCRNASHQTPLHLACLSQSIGTVDLLISYGANVNAVYRDGR 333
            |||||..:...:|.::||:|.|..|..:|.:::|||.|..|....:|.||..:.|.::.:..|||
Mouse    90 ALHLATISCQPQCVKVLLQHGANEDAVDAENRSPLHWAASSGCASSVLLLCDHEAFLDVLDNDGR 154

  Fly   334 TAL-------HAAIVKQSRSLDCCNALLKAGADVNKADNYGYTPLHIAALNEFSSCVYTFIEHGA 391
            |.|       ||||         |:.||:.||.||..|....:.|.:|.....:......:.|||
Mouse   155 TPLMIASLGGHAAI---------CSQLLQRGARVNVTDKDDKSALILACEKGSAEVAELLLSHGA 210

  Fly   392 DITARTDGRVSALSFIVRRTPEIIPKLMQK 421
            |..|......:||.:.:|...:.:.:|:|:
Mouse   211 DAGAVDSLGHNALHYALRTQDKELWRLLQQ 240

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
pyxNP_612015.1 Ank_4 99..153 CDD:290365 3/13 (23%)
ANK repeat 102..130 CDD:293786
ANK 127..252 CDD:238125 20/112 (18%)
ANK repeat 132..163 CDD:293786 3/23 (13%)
Ank_2 137..226 CDD:289560 15/86 (17%)
ANK repeat 166..196 CDD:293786 6/29 (21%)
ANK 198..319 CDD:238125 35/120 (29%)
ANK repeat 200..229 CDD:293786 4/28 (14%)
Ank_2 203..296 CDD:289560 25/92 (27%)
ANK repeat 231..262 CDD:293786 10/30 (33%)
ANK 268..387 CDD:238125 41/125 (33%)
ANK repeat 268..296 CDD:293786 12/27 (44%)
Ank_2 270..364 CDD:289560 36/100 (36%)
ANK repeat 298..329 CDD:293786 9/30 (30%)
ANK repeat 331..364 CDD:293786 16/39 (41%)
Ank_5 353..404 CDD:290568 14/50 (28%)
ANK repeat 366..396 CDD:293786 6/29 (21%)
Ion_trans 556..734 CDD:278921
Ankrd35NP_001074608.1 ANK <24..107 CDD:238125 28/114 (25%)
ANK repeat 24..51 CDD:293786 8/36 (22%)
ANK repeat 53..84 CDD:293786 11/51 (22%)
ANK 81..206 CDD:238125 43/134 (32%)
ANK repeat 86..117 CDD:293786 13/31 (42%)
ANK repeat 119..150 CDD:293786 9/30 (30%)
ANK repeat 152..183 CDD:293786 16/39 (41%)
ANK repeat 185..216 CDD:293786 7/30 (23%)
Ank_2 190..>251 CDD:315466 12/51 (24%)
SMC_N <710..>996 CDD:330553
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
11.000

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