DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7028 and hipk3

DIOPT Version :9

Sequence 1:	NP_001286884.1	Gene:	CG7028 / 38032	FlyBaseID:	FBgn0027587	Length:	912	Species:	Drosophila melanogaster
Sequence 2:	XP_012816854.1	Gene:	hipk3 / 780181	XenbaseID:	XB-GENE-1010053	Length:	1217	Species:	Xenopus tropicalis

Alignment Length:	536	Identity:	141/536 - (26%)
Similarity:	243/536 - (45%)	Gaps:	86/536 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   434 NIDILEEDDEERIIELRRKKREEL-LKKLGTGQESPAPHNSVSYESRSTS-----QGSSQRERPL 492
            :|..|:.:....:...|..:|.:| .:.:|..|  |:..|...:::::||     |.:..:..|:
Frog    48 SIKKLKVEPSSCLYNKRSYQRTDLNARSIGFAQ--PSNKNRAPFQTKNTSDKPRHQAAVSKTSPV 110

  Fly   493 RTPSPTMPCPNPLISEIPKD-REDMDNST---------SQKTCSAKEKRNEWDMFADQDVDSNFD 547
             |.:........|.::..:| :|::...|         :.:.|..|.|..:   |.:|:......
Frog   111 -TLNTNTGASGDLAAQAQQDPKEELTVGTPESGSDLLDAHQRCGLKRKSKD---FENQNGTMQIV 171

  Fly   548 VSRKISPNTIVQNKHQHENPALT-----DNWDDAEGYYRVRIGEVL---DNRYLVNGYTGQGVFS 604
            ....|.|..:..|.........|     .:....:|.|::.:.|||   .|.|.|..:.|:|.|.
Frog   172 DELSILPAMLPNNAANQVTVVATTGTSKQSTASGDGDYQLMLHEVLCSVKNTYEVLDFLGRGTFG 236

  Fly   605 NVV----RGRDQARGQANVAIKIIRNNEIMHKTGLRELEILKKLNDADPEDRFHCLRLYRHFFHK 665
            .||    ||.::.     ||:||::|:....:.|..|:.||.:|:: :..|.|:.:|.|..|.|:
Frog   237 QVVKCWRRGTNEV-----VAVKILKNHPSYARQGQIEMGILARLSN-ENADEFNFVRAYECFQHR 295

  Fly   666 QHLCMVFEPLAMNLREVLKKYGKNVGLHIKAVRSYTQQLFLALKLLKKTGILHADIKPDNILVNE 730
            .|.|:|||.|..||.:.||: .|...|.:|.:|:..||:..|||.||..|::|||:||:||::.:
Frog   296 NHTCLVFEMLEQNLYDFLKQ-NKFSPLPLKVIRAILQQVATALKKLKSLGLIHADLKPENIMLVD 359

  Fly   731 ---NNLILKLCDFGSASAISDNEITPYLVSRFYRSPEIILGIPYDYGIDTWSAGCTIYELYTGKI 792
               ....:|:.||||||.:|....:.||.||:||:||:|||:|:...||.||.||.|.||:.|..
Frog   360 PVRQPYRVKVIDFGSASYVSKTVCSTYLQSRYYRAPEVILGLPFCEAIDMWSLGCVIAELFLGWP 424

  Fly   793 LFSGKSNNQMLKFFMDVKGKIPNRIIRKGQFREQHF---------------------------DQ 830
            |:.|......:::....:|...:.:|..|....:.|                           .:
Frog   425 LYPGAQEYDQIRYISQTQGLPGDSLINAGTKTSRFFCREPDAPYPSWRLKTLEEHEAETGIKSKE 489

  Fly   831 SCNFLYHEIDKLTEREKIVVMPVVKPSRSLQQELIADQNLPDDQHRKVTQLKDLLENMFALDPAK 895
            :..::::.:|::.....:|.:.        ..:|:|::   .|:...|.    ||:.|..:|..|
Frog   490 TRKYIFNNLDEIVHVNMMVDLD--------GSDLMAEK---ADRREFVA----LLKKMLMIDADK 539

  Fly   896 RISLNQALVHPFIQEK 911
            |||....|...||..|
Frog   540 RISPADTLSQSFITMK 555

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7028	NP_001286884.1	STKc_PRP4	591..908	CDD:271037	105/350 (30%)
CG7028	NP_001286884.1	S_TKc	599..908	CDD:214567	103/342 (30%)
hipk3	XP_012816854.1	STKc_HIPK3	223..552	CDD:271131	105/350 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000