Protein Alignment Prp4k and prpf4ba

DIOPT Version :10

• Sequence 1: NP_001286884.1
• Gene: Prp4k / 38032
• FlyBaseID: FBgn0027587
• Length: 912
• Species: Drosophila melanogaster
• Sequence 2: XP_017207374.1
• Gene: prpf4ba / 393182
• ZFINID: ZDB-GENE-040426-947
• Length: 986
• Species: Danio rerio
• Alignment Length: 1015
• Identity: 420/1015 - (41%)
• Similarity: 560/1015 - (55%)
• Gaps: 173/1015 - (17%)

  Fly     5 KSYDSSNNSETEE-RRAKHKKAKKHKKHKKSSTGKTE---KDRHVHKKQKKAKKRPHRTSESTNE 65
            |..|:.:.:..|: ::.|||...||||||.||..:.:   |.:|.||::.:...|..|...::.|
Zfish    38 KKADNMDFARVEKHKKRKHKHRSKHKKHKHSSPDERDQKHKYKHKHKRKHRDSFRDDRECSTSYE 102

  Fly    66 SDAPENAKLKLSQNCGL-----------SSKFTEIMQKASRNGADFRVGKPLLPTDPSSLVEEIT 119
            ..|....:.:|.....|           :....|:|:.:.::|    :|..|...:..|...|:.
Zfish   103 GAADSPKRFRLDDLAALEDLEKQRAMIQAELDNELMEGSVQSG----MGLILQGYNSDSEDGEVQ 163

  Fly   120 KTIQN-----KMLPVLEVASSSS---ESDVPADAASPIILSIIEDELNLEELMRQKALLQAR--- 173
            :.::|     |.|..|.....:.   :.|...|..   ..|::|.....||:..|....:.|
Zfish   164 EAVRNGEQQRKDLDELVTVKGNGRKLQQDYVNDEQ---FYSVLEGRTMSEEVTVQSHKSEKRESM 225

  Fly   174 --LGAYMSD-----PEAEDKGDLLPHTHSQQLVVHTKSVLKAVTSVPQPQPSKSAAPLATATSK- 230
              ||..:|:     .|.:::........|:.....:||.:|:     :..||.||.....:.::
Zfish   226 TGLGIKISERPSGPSETKERRRSRSTDRSKDRSRRSKSPVKS-----KEVPSSSATSNRKSNTRP 285

  Fly   231 ------HANIKKSTTHNSNESDVIL-------------LDDSSGGQRTPSPT----PEK------ 266
                  |.:..:|:...|.|....|             |.:.|.|:...||:    |::
Zfish   286 EEQAVDHRSSSRSSKSGSKERSTSLPEVDRDKKPVKAPLKEVSSGKENRSPSRKQGPDRLSPTVQ 350

  Fly   267 RRRHASP--LPAAPRS-RCRRDRRSRDRDRSPPRRRASDQQTQVRPRSRNRNMEDLRQEINRDKQ 328
            .|.|.||  ||....: |..|..||...:|||||            |.|:|::|..|:|  .::|
Zfish   351 PRSHRSPERLPVVQNTDRASRQDRSTCHNRSPPR------------RGRSRSVERRRRE--EERQ 401

  Fly   329 RERRDHSRDRDRRGLDRPPPP-----------------------TDMRPGRARERDVRPSRMQRS 370
            |...|..|.||..|..|...|                       :...|.|.|||| |..|.|..
Zfish   402 RLSSDRMRSRDMAGAHREDSPSISSRRRLNHSPLRRRSRSPRRRSSRSPLRHRERD-RMDRRQPV 465

  Fly   371 HSRSKFESDRRRERERQKDRDRGGGRVGARSGTDNGDRDRYKGSLSEGQNKLDKESSDEEVNVNI 435
            .|||: |..|||.:||:                     |.:|||||||. |.::|.|||||..:.
Zfish   466 RSRSQ-ERRRRRSKERE---------------------DMFKGSLSEGM-KAEQEDSDEEVLEDY 507

  Fly   436 DILEEDDEERIIELRRKKREELLKKLGTGQESPAPHNSVSYESRSTSQGSSQRERPLRTPSPTMP 500
            |: :|:|||.:||.||.:|..:::|.       .|.|..|..|..:..||.|.....|:||
Zfish   508 DV-DEEDEEALIEQRRLQRLAIMQKY-------KPVNEDSNMSGLSDHGSPQSSTHSRSPS---- 560

  Fly   501 CPNPLISEIPKD-----REDMD----------NSTSQKTCSAKEKRNEW-DMFADQD--VDSNFD 547
             |:.::..:..|     :|::|          :..||:...|..|:... |||.:.|  ..:.||
Zfish   561 -PDDILERVAADVKAYEQENLDTFEDNVKAKYSLVSQEKNGANSKKPPAPDMFTESDDMFAAYFD 624

  Fly   548 VSRKISPNTIVQNKHQHENPALTDNWDDAEGYYRVRIGEVLDNRYLVNGYTGQGVFSNVVRGRDQ 612
            .:|..:...   .|...|||:|.|||.||||||||.||||||.||.|.|||||||||||:|.||.
Zfish   625 SARLRAAGI---GKDFKENPSLRDNWTDAEGYYRVNIGEVLDKRYAVYGYTGQGVFSNVIRARDL 686

  Fly   613 ARGQANVAIKIIRNNEIMHKTGLRELEILKKLNDADPEDRFHCLRLYRHFFHKQHLCMVFEPLAM 677
            ||....||:|||||||:|.||||:|||.||||||||.:|:||||||:|||:||||||:|||||:|
Zfish   687 ARANQEVAVKIIRNNEMMQKTGLKELEFLKKLNDADADDKFHCLRLFRHFYHKQHLCLVFEPLSM 751

  Fly   678 NLREVLKKYGKNVGLHIKAVRSYTQQLFLALKLLKKTGILHADIKPDNILVNENNLILKLCDFGS 742
            ||||||:||||:|||||||||||:||||||||.||:..|||||||||||||||...|||||||||
Zfish   752 NLREVLRKYGKDVGLHIKAVRSYSQQLFLALKHLKRCNILHADIKPDNILVNEPKTILKLCDFGS 816

  Fly   743 ASAISDNEITPYLVSRFYRSPEIILGIPYDYGIDTWSAGCTIYELYTGKILFSGKSNNQMLKFFM 807
            ||.::||:|||||||||||:||||:|..||||||.||.|||:||||||||||.||:||.|||..|
Zfish   817 ASHVADNDITPYLVSRFYRAPEIIIGKSYDYGIDMWSVGCTLYELYTGKILFPGKTNNHMLKLNM 881

  Fly   808 DVKGKIPNRIIRKGQFREQHFDQSCNFLYHEIDKLTEREKIVVMPVVKPSRSLQQELIADQNLPD 872
            |:|||:||::||||.|::|||||:.||||.|:||:||||||.||..:.|::.|..:::..|.||:
Zfish   882 DLKGKLPNKMIRKGLFKDQHFDQNLNFLYTEVDKVTEREKITVMSTINPTKDLSMDMVGRQALPE 946

  Fly   873 DQHRKVTQLKDLLENMFALDPAKRISLNQALVHPFIQEKM 912
            ||.:||.||||||:.:..|||||||::||||.||||||::
Zfish   947 DQRKKVGQLKDLLDQILMLDPAKRITINQALQHPFIQERI 986

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Prp4k	NP_001286884.1	STKc_PRP4	591..908	CDD:271037	229/316 (72%)
prpf4ba	XP_017207374.1	STKc_PRP4	665..982	CDD:271037	229/316 (72%)