DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7028 and Hipk

DIOPT Version :9

Sequence 1:	NP_001286884.1	Gene:	CG7028 / 38032	FlyBaseID:	FBgn0027587	Length:	912	Species:	Drosophila melanogaster
Sequence 2:	NP_001369036.1	Gene:	Hipk / 38070	FlyBaseID:	FBgn0035142	Length:	1409	Species:	Drosophila melanogaster

Alignment Length:	548	Identity:	148/548 - (27%)
Similarity:	246/548 - (44%)	Gaps:	80/548 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   393 GGGRVGARSGTDNGDRDRYKGSLSEGQNKLDKESSDEEVNVNIDILEEDDEERIIELRRKKREEL 457
            |||..|..||...|        ||.   :......|:.|....|.....:::: .:|::::::.:
  Fly    19 GGGGSGFCSGLGAG--------LSV---RATSFYGDQTVTATTDGTRHQEQQQ-QQLQQQQQQHI 71

  Fly   458 LKKLGTGQESPAPHNSVSYESRSTSQGSSQRERPLRTPSPTMPCPNPLISEIPKDREDMDNSTSQ 522
            |::         |..|.|..|.:.: .:|:|:|........:...|.  |..|..::|...:...
  Fly    72 LRQ---------PATSASTSSVAAA-ATSKRKRQTDCDCGCVDSYNS--SHGPPVQQDSSAAAGA 124

  Fly   523 KTCSAKEKRNEWDMFADQDVDSNFDVSRKISPNTIVQNKHQHEN--PALTDNWDDAEGYYRVRIG 585
            .:..:|..       :....|....:|...:.:|.|.....|.|  |....:...|:|.|::...
  Fly   125 GSVGSKAG-------SGPGPDGIGPISSLKTAHTKVATSGGHANTQPPSKRSSSGADGDYQLVQH 182

  Fly   586 EV---LDNRYLVNGYTGQGVFSNVV----RGRDQARGQANVAIKIIRNNEIMHKTGLRELEILKK 643
            ||   |...|.|..:.|:|.|..||    ||..:.     |||||::|:....:.|..|:.||.:
  Fly   183 EVLYSLSAEYEVLEFLGRGTFGQVVKCWKRGTSEI-----VAIKILKNHPSYARQGQIEVSILSR 242

  Fly   644 LNDADPEDRFHCLRLYRHFFHKQHLCMVFEPLAMNLREVLKKYGKNVGLHIKAVRSYTQQLFLAL 708
            |:. :..|.|:.:|.:..|.||.|.|:|||.|..||.:.||: .|...|.:|.:|...:|:..||
  Fly   243 LSQ-ENADEFNFVRAFECFQHKNHTCLVFEMLEQNLYDFLKQ-NKFSPLPLKYIRPILEQVLTAL 305

  Fly   709 KLLKKTGILHADIKPDNILVNE---NNLILKLCDFGSASAISDNEITPYLVSRFYRSPEIILGIP 770
            ..||:.|::|||:||:||::.:   ....:|:.||||||.:|......||.||:||:||||||:|
  Fly   306 LKLKQLGLIHADLKPENIMLVDPVRQPYRVKVIDFGSASHVSKTVCNTYLQSRYYRAPEIILGLP 370

  Fly   771 YDYGIDTWSAGCTIYELYTGKILFSGKSNNQMLKFFMDVKGKIPNRIIRKGQFREQHFDQSCNFL 835
            :...||.||.||.:.||:.|..|:.|.|....:::....:|.....::...       .::..|.
  Fly   371 FCEAIDMWSLGCVVAELFLGWPLYPGSSEFDQIRYISQTQGLPTEHMLNSA-------SKTSKFF 428

  Fly   836 YHEID--------KLTEREKIVVMPVVKPSR-------------SLQQELIADQNLPDDQHRKVT 879
            |.::|        |.||..:.......|.:|             ::..:|...|.|.:...|:
  Fly   429 YRDVDSTYPFWRLKTTEEHEAETNTKSKEARKYIFNCLDDIGQVNVPTDLEGGQLLAEKTDRR-- 491

  Fly   880 QLKDLLENMFALDPAKRISLNQALVHPF 907
            :..|||:.|..:|..:|::..:||.|.|
  Fly   492 EFIDLLKRMLTIDQERRLTPAEALNHSF 519

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7028	NP_001286884.1	STKc_PRP4	591..908	CDD:271037	109/345 (32%)
CG7028	NP_001286884.1	S_TKc	599..908	CDD:214567	107/337 (32%)
Hipk	NP_001369036.1	STKc_HIPK	192..520	CDD:271113	109/344 (32%)
Hipk	NP_001369036.1	PHA03378	<1080..1327	CDD:223065
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0667
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810