DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7028 and lkh1

DIOPT Version :9

Sequence 1:	NP_001286884.1	Gene:	CG7028 / 38032	FlyBaseID:	FBgn0027587	Length:	912	Species:	Drosophila melanogaster
Sequence 2:	NP_001018187.2	Gene:	lkh1 / 3361532	PomBaseID:	SPAC1D4.11c	Length:	690	Species:	Schizosaccharomyces pombe

Alignment Length:	473	Identity:	128/473 - (27%)
Similarity:	219/473 - (46%)	Gaps:	67/473 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   471 HNSVSYESRSTSQGSSQRERPLRTPSPTM--------PCPNPLISEIPKDREDMDN-----STSQ 522
            |.||:| |.:.|..::....||   |||:        |...|..:.:.:...:.:.     |.|.
pombe   246 HKSVNY-SVTPSSINNHTAVPL---SPTLAVWLPMTQPTFQPPSANVYQPASNANQVITPVSISD 306

  Fly   523 KTCSAKEKRNEWDMFADQDVDSNFDVSRKISPNTIVQNKHQHENPAL-TDNWDDAEGYYRVRIGE 586
            .....|.||..|..:...|         :::...:      |:..|. ...:||.:|:|:|....
pombe   307 YRPPKKRKRAAWPPYKKVD---------RVNVPVV------HDTTAFDPSTFDDDDGHYKVVPNS 356

  Fly   587 VLDNRYLVNGYTGQGVFSNVVRGRDQARGQANVAIKIIRNNEIMHKTGLRELEILKKLNDADPED 651
            ...|||.|....|.|.|..|::..||:.|: :.|||:.|......:..|.||.:|:.:..:||.:
pombe   357 KFANRYTVVRLLGHGTFGKVIQCYDQSTGR-HCAIKVTRAIPKYREASLIELRVLQTIAHSDPTN 420

  Fly   652 RFHCLRLYRHFFHKQHLCMVFEPLAMNLREVLKKYGKNVGLHIKAVRSYTQQLFLALKLLKKTGI 716
            ...|::|..:|.:::|:|:|.:....::.:.||. ...:...:|.::..:||||.::..|...|:
pombe   421 ENKCIQLRDYFDYRKHICIVTDLFGWSVFDFLKN-NNYIPFPLKHIQMLSQQLFKSVAFLHSLGL 484

  Fly   717 LHADIKPDNILV-------------NENNLILKLC-----DFGSASAISDNEITPYLVSRFYRSP 763
            :|.|:||:|:|:             |.:..:|..|     |||||: ..|...:..:.:|.||:|
pombe   485 VHTDLKPENVLLVSNASRTIRLPYRNYSQKVLNSCEIRLIDFGSAT-FEDEYHSSVVSTRHYRAP 548

  Fly   764 EIILGIPYDYGIDTWSAGCTIYELYTGKILFSGKSNNQMLKFFMDVKGKIPNRIIRKGQFREQHF 828
            |||||:.:.|..|.||.||.:.||:||:.||....:::.|.....:.|.....:|.:.....|.|
pombe   549 EIILGLGWSYPCDVWSIGCILVELFTGQALFQTHEDSEHLCMMEKILGPFDRNMISRSSRTSQRF 613

  Fly   829 DQSCNFLYHEIDKLTEREKIVVMPVVKPSRSLQQ-ELIADQNLPDDQHRKVTQLKDLLENMFALD 892
            .:|...:.:.:.. |.::.|..:      :|||. |.|...:.|:     |..|.|||:.:|..|
pombe   614 FKSDGKVRYPLSN-TPKKSINYL------QSLQTLEQIFAVSSPE-----VALLLDLLKKVFVYD 666

  Fly   893 PAKRISLNQALVHPFIQE 910
            |.:||:..:||.|||..:
pombe   667 PKRRITAKEALWHPFFTQ 684

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7028	NP_001286884.1	STKc_PRP4	591..908	CDD:271037	99/335 (30%)
CG7028	NP_001286884.1	S_TKc	599..908	CDD:214567	96/327 (29%)
lkh1	NP_001018187.2	E_Pc_C	<104..198	CDD:284226
		PKc_CLK	349..682	CDD:271036	102/347 (29%)
		S_TKc	362..682	CDD:214567	98/334 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0667
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810