DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7028 and Hipk4

DIOPT Version :9

Sequence 1:	NP_001286884.1	Gene:	CG7028 / 38032	FlyBaseID:	FBgn0027587	Length:	912	Species:	Drosophila melanogaster
Sequence 2:	NP_001019947.1	Gene:	Hipk4 / 308449	RGDID:	1307541	Length:	616	Species:	Rattus norvegicus

Alignment Length:	370	Identity:	108/370 - (29%)
Similarity:	175/370 - (47%)	Gaps:	61/370 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   570 TDNWDDAEGYYRVRIGEVLDNRYLVNGYTGQGVFSNVVRGRDQARGQANVAIKIIRNNEIMHKTG 634
            ||.:|         |.|||          |:|.|..|.:|..::.|:. |||||::|:....:..
  Rat     8 TDCYD---------IIEVL----------GKGTFGEVAKGWRRSTGEM-VAIKILKNDAYRSRII 52

  Fly   635 LRELEILKKLNDADPEDRFHCLRLYRHFFHKQHLCMVFEPLAMNLREVLKKYGKNVGLHIKAVRS 699
            ..||::|:.:...|| |..|.:|....|.......:|||.|..||.| .:|......|..:.:|:
  Rat    53 KNELKLLRCVRGLDP-DEAHVIRFLEFFHDALKFYLVFELLEQNLFE-FQKENNFAPLPARHIRT 115

  Fly   700 YTQQLFLALKLLKKTGILHADIKPDNILVNENN---LILKLCDFGSASAISDNEIT--PYLVSRF 759
            .|.|:..||..||:..|:|||:||:||::.:..   ..:|:.||||||..|:....  ||:.|||
  Rat   116 VTLQVLRALARLKELAIIHADLKPENIMLVDQTRCPFRVKVIDFGSASIFSEVRYVKEPYIQSRF 180

  Fly   760 YRSPEIILGIPYDYGIDTWSAGCTIYELYTGKILFSGKSNNQMLKFFMDVKGKIPNRIIRKGQFR 824
            ||:|||:||:|:...:|.||.||.:.||:.|..|:.|.:....:::..:.:| :|...:.....:
  Rat   181 YRAPEILLGLPFCEKVDVWSLGCVMAELHLGWPLYPGNNEYDQVRYICETQG-LPKPHLLHAARK 244

  Fly   825 EQHF---------------DQSCNFLYHEIDKLTEREKIVVMPVVKPSRSLQQ-------ELIAD 867
            ..||               ..|.::|.....:..||.|.::       :||.|       ..:..
  Rat   245 AHHFFKRNPHPDATNPWQLKSSADYLAETKVRPLERRKYML-------KSLDQIETVNGGGAVNR 302

  Fly   868 QNLPD----DQHRKVTQLKDLLENMFALDPAKRISLNQALVHPFI 908
            .:.||    .:|..:..:.:|::.|...:..:|||.:.||.|||:
  Rat   303 LSFPDREALAEHADLKSMVELIKRMLTWESHERISPSAALRHPFV 347

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7028	NP_001286884.1	STKc_PRP4	591..908	CDD:271037	100/347 (29%)
CG7028	NP_001286884.1	S_TKc	599..908	CDD:214567	100/339 (29%)
Hipk4	NP_001019947.1	PKc_like	11..347	CDD:419665	105/365 (29%)
Hipk4	NP_001019947.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	487..616
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0667
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900