Protein Alignment CG7028 and mbk-1

DIOPT Version :9

• Sequence 1: NP_001286884.1
• Gene: CG7028 / 38032
• FlyBaseID: FBgn0027587
• Length: 912
• Species: Drosophila melanogaster
• Sequence 2: NP_510460.2
• Gene: mbk-1 / 181578
• WormBaseID: WBGene00003149
• Length: 882
• Species: Caenorhabditis elegans
• Alignment Length: 720
• Identity: 174/720 - (24%)
• Similarity: 299/720 - (41%)
• Gaps: 170/720 - (23%)

  Fly   278 PRSRCRRDRRSRDRDRSPPRRRASDQQTQVRPRSRNRNMEDLR-QEINRDKQRERRDH------- 334
            |.|.....::.......||....:...|:  |.:.:..::|:: .|:.:.::::.:.|
 Worm    17 PSSSYSNTQQHSQMTNLPPINHNNLCDTE--PMNEDFQLQDVQADELQKQQKQQEQQHIQQQNAQ 79

  Fly   335 -----SRDRDRRGLDRPPPP-TDMRPG------RARERDVRPS--RMQRSHSRSKFESDRRRERE 385
                 ||......|..|.|| |.::..      :.....|||.  |:..:::.:........|::
 Worm    80 RFIAQSRQPHSNILRFPQPPITSIKTNSHAFYPQQEVTQVRPKKHRVSMTNAEAALTPGMPPEKQ 144

  Fly   386 RQKDRD----------RGGGRVGARSGTDNGDRDRYKGSLSEGQNKLD----KESSD-----EEV 431
            ..|.|:          .|.|.:|....:.:...     .:.:.:|..|    |.:||     :.:
 Worm   145 AAKKRNIGQFSTDTVPAGIGMIGIPFESTSKPL-----QIQQFRNPQDAPVRKLTSDLIKTYKAI 204

  Fly   432 NVNIDILEEDDEERIIELRRKKREELLKKLGTGQESPAP-------HNSVSYESRST--SQGSSQ 487
            |.:..:.::      :...|.|.::..|..|:...|.|.       ||::...|...  .|.:.|
 Worm   205 NESFYLRKQ------VRRDRHKSQDAGKPKGSKDGSGASLTDTFSIHNAIPITSSDNHYQQDAHQ 263

  Fly   488 RERPL----RTPSPTMPCPNPLISEIPKDREDMDNSTSQKTCSAKEKRNEWDMFADQDVDSNFDV 548
            ...||    ..|:.||..|       .:...|:.....||:.......|.:|       |.|:|
 Worm   264 NAPPLLDTNAPPTSTMVVP-------MRTETDLQQQQRQKSSRGGPYNNGYD-------DQNYD- 313

  Fly   549 SRKISPNTIVQNKHQHENPALTDNWDDAEGYYRVRIGEVLDNRYLVNGYT--GQGVFSNVVRGRD 611
                                           |.::.||:.|.||::...|  |:|.|..|.:..|
 Worm   314 -------------------------------YILKNGEIFDKRYVILSDTPVGKGSFGQVTKAYD 347

  Fly   612 QARGQANVAIKIIRNNEIMHKTGLRELEILKKLNDADPEDRFHCLRLYRHFFHKQHLCMVFEPLA 676
             ...:..||||||:|.:........|:.:|:..|..|.:::::.:.|..||.|:.|||:|||.|:
 Worm   348 -TLNKEEVAIKIIKNKKTFFDQAQIEIHLLELTNAHDKDNKYNIVTLKGHFVHRAHLCLVFELLS 411

  Fly   677 MNLREVLKKYGKNVGLHIKAVRSYTQQLFLALKLLK--KTGILHADIKPDNI-LVNENNLILKLC 738
            .||.::||..... |:.:...|.:.|||...|..|.  :..|:|.|:||:|: |||.....:::.
 Worm   412 YNLYDLLKNTSFR-GVSLNLARKFAQQLGKTLLFLSSPELSIIHCDLKPENVLLVNAKRSQIRVI 475

  Fly   739 DFGSASAISDNEITPYLVSRFYRSPEIILGIPYDYGIDTWSAGCTIYELYTGKILFSGKSN-NQM 802
            |||| |..:.:.|..|:.||||||||::|||.||..||.||.||.:.|::||:.||:|.|. :||
 Worm   476 DFGS-SCQTGHRIYQYIQSRFYRSPEVLLGIAYDTKIDMWSLGCILVEMHTGEPLFAGSSEVDQM 539

  Fly   803 LKFFMDVKGKIPNRIIRKGQFREQHFDQSCNFLY---------------------HEIDKLTE-- 844
            :| .::|.|..|..::..|....::||::.:.:|                     |||..:|.
 Worm   540 MK-IVEVLGMPPKEMLDIGPKTHKYFDKTEDGIYYCKKTRDGYRHTYKAPGARKLHEILGVTSGG 603

  Fly   845 ---REKIVVMPVVKPSRSLQQELIADQNLPDDQHRKVTQLKDLLENMFALDPAKRISLNQALVHP 906
               |.      :.:|..|::.               .::.|||::.|...||.:|||....:.||
 Worm   604 PGGRR------LGEPGHSVED---------------YSKFKDLIKRMLQFDPKQRISPYYVVRHP 647

  Fly   907 FIQEK 911
            |:::|
 Worm   648 FLKQK 652

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7028	NP_001286884.1	STKc_PRP4	591..908	CDD:271037	111/348 (32%)
		S_TKc	599..908	CDD:214567	108/338 (32%)
mbk-1	NP_510460.2	PKc_DYRK1	312..651	CDD:271128	117/395 (30%)
		S_TKc	326..649	CDD:214567	110/347 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0667
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810