Protein Alignment CG7028 and CLK2

DIOPT Version :9

• Sequence 1: NP_001286884.1
• Gene: CG7028 / 38032
• FlyBaseID: FBgn0027587
• Length: 912
• Species: Drosophila melanogaster
• Sequence 2: NP_001281267.1
• Gene: CLK2 / 1196
• HGNCID: 2069
• Length: 499
• Species: Homo sapiens
• Alignment Length: 605
• Identity: 166/605 - (27%)
• Similarity: 251/605 - (41%)
• Gaps: 159/605 - (26%)

  Fly   331 RRDHSRDRDRRGLDRPPPPTDMRPGRARERDVRPSRMQRSHSRSKFESDRRRERERQKDRDRGGG 395
            ||.||.:|..||..|              ...|..:.:|..|||...|..|..|.|::|    ..
Human     5 RRYHSSERGSRGSYR--------------EHYRSRKHKRRRSRSWSSSSDRTRRRRRED----SY 51

  Fly   396 RVGARSGTDNGDRD------RYKGSLSEGQNKLDKESSDEEVNVNIDILEEDDEERIIELRRKKR 454
            .|.:||..|:...|      ||.||........|:.          |...:.|.....|.:|:
Human    52 HVRSRSSYDDRSSDRRVYDRRYCGSYRRNDYSRDRG----------DAYYDTDYRHSYEYQRE-- 104

  Fly   455 EELLKKLGTGQESPAPHNSVSYESRSTSQGSSQRERPLRTPSPTMPCPNPLISEIPKDREDMDNS 519
                             || ||.|:.:|:...:|.|
Human   105 -----------------NS-SYRSQRSSRRKHRRRR----------------------------- 122

  Fly   520 TSQKTCSAKEKRNEWDMFADQDVDSNFDVSRKISPNTIVQNKHQHENPALTDNWDDAEGYYRVRI 584
                      :|:                      .|..::..||.:.......|||||:....:
Human   123 ----------RRS----------------------RTFSRSSSQHSSRRAKSVEDDAEGHLIYHV 155

  Fly   585 GEVLDNRYLVNGYTGQGVFSNVVRGRDQARGQANVAIKIIRNNEIMHKTGLRELEILKKLNDADP 649
            |:.|..||.:....|:|.|..||:..|..||.|.||:|||:|.|...:....|:.:|:|:|:.||
Human   156 GDWLQERYEIVSTLGEGTFGRVVQCVDHRRGGARVALKIIKNVEKYKEAARLEINVLEKINEKDP 220

  Fly   650 EDRFHCLRLYRHFFHKQHLCMVFEPLAMNLREVLKKYGKNVGLHIKAVRSYTQQLFLALKLLKKT 714
            :::..|::::..|.:..|:|:.||.|.::..:.||. ...:...|..||....||..|:|.|...
Human   221 DNKNLCVQMFDWFDYHGHMCISFELLGLSTFDFLKD-NNYLPYPIHQVRHMAFQLCQAVKFLHDN 284

  Fly   715 GILHADIKPDNIL-VNEN-----NL------------ILKLCDFGSASAISDNEITPYLVS-RFY 760
            .:.|.|:||:||| ||.:     ||            .:::.|||||:  .|:|....:|| |.|
Human   285 KLTHTDLKPENILFVNSDYELTYNLEKKRDERSVKSTAVRVVDFGSAT--FDHEHHSTIVSTRHY 347

  Fly   761 RSPEIILGIPYDYGIDTWSAGCTIYELYTGKILFSGKSNNQMLKFFMDVKGKIPNRIIRKGQFRE 825
            |:||:||.:.:....|.||.||.|:|.|.|..||....|.:.|.....:.|.||:|:|||  .|:
Human   348 RAPEVILELGWSQPCDVWSIGCIIFEYYVGFTLFQTHDNREHLAMMERILGPIPSRMIRK--TRK 410

  Fly   826 QHFDQSCNFLYH---EIDKLTEREKIVVMPVVKPSRSLQQELIADQNLPDDQHRKVTQLKDLLEN 887
            |      .:.|.   :.|:.|...: .|....||   |::.|.::.    ::|.   ||.||:|:
Human   411 Q------KYFYRGRLDWDENTSAGR-YVRENCKP---LRRYLTSEA----EEHH---QLFDLIES 458

  Fly   888 MFALDPAKRISLNQALVHPF 907
            |...:||||::|.:||.|||
Human   459 MLEYEPAKRLTLGEALQHPF 478

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7028	NP_001286884.1	STKc_PRP4	591..908	CDD:271037	115/339 (34%)
		S_TKc	599..908	CDD:214567	113/331 (34%)
CLK2	NP_001281267.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..67		23/79 (29%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	101..143		13/122 (11%)
		PKc_CLK2	150..479	CDD:271117	117/351 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0667
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810