Protein Alignment NitFhit and VNN1

DIOPT Version :9

• Sequence 1: NP_525122.1
• Gene: NitFhit / 38029
• FlyBaseID: FBgn0024945
• Length: 460
• Species: Drosophila melanogaster
• Sequence 2: NP_004657.2
• Gene: VNN1 / 8876
• HGNCID: 12705
• Length: 513
• Species: Homo sapiens
• Alignment Length: 344
• Identity: 71/344 - (20%)
• Similarity: 125/344 - (36%)
• Gaps: 116/344 - (33%)

  Fly   102 LAKCNKIWISLGGVHERNDQK---------------IFNAHVLLNEKGELAAVYRKLHMFDVTTK 151
            |||.|.|::    |....|:|               .:|..|:.:.:|:|.|.|.|.::|....:
Human   127 LAKNNSIYV----VANIGDKKPCDTSDPQCPPDGRYQYNTDVVFDSQGKLVARYHKQNLFMGENQ 187

  Fly   152 EVRLRESDTVTPGYCLERPVSTPVGQIGLQICYDLRFAEPAV-LLRKLGANLLTYPSAFT----- 210
            ....:|.:.||        .:|..|..|:..|:|:.|.:||| |::....:.:.:|:|:.
Human   188 FNVPKEPEIVT--------FNTTFGSFGIFTCFDILFHDPAVTLVKDFHVDTIVFPTAWMNVLPH 244

  Fly   211 YATGKAH--WEILLRARAIETQCFVVAAAQIG-----------WHNQKRQSWG------------ 250
            .:..:.|  |.:.:|...:.:.....:....|           :|...:...|
Human   245 LSAVEFHSAWAMGMRVNFLASNIHYPSKKMTGSGIYAPNSSRAFHYDMKTEEGKLLLSQLDSHPS 309

  Fly   251 HSMIVSPWGNVLADCSEQELDIGTAE------------VDLSVLQSLY----QTMPCF------E 293
            ||.:|: |.:..:  |.:.|..|..|            |.|:.:...|    :.:.|.      |
Human   310 HSAVVN-WTSYAS--SIEALSSGNKEFKGTVFFDEFTFVKLTGVAGNYTVCQKDLCCHLSYKMSE 371

  Fly   294 HRRNDIYALTAYNLRSKEPTQDRPFATNIVDKRTIFYESEHCFAFTNLRCVVKGHVLVSTKRVTP 358
            :..|::|||.|::            ..:.|:.|   |..:.|   |.|:|          |....
Human   372 NIPNEVYALGAFD------------GLHTVEGR---YYLQIC---TLLKC----------KTTNL 408

  Fly   359 RLCGLDCAEMA----DMFT 373
            ..|| |.||.|    :||:
Human   409 NTCG-DSAETASTRFEMFS 426

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NitFhit	NP_525122.1	nit	34..296	CDD:143596	50/261 (19%)
		FHIT	317..436	CDD:238606	16/61 (26%)
VNN1	NP_004657.2	biotinidase_like	25..330	CDD:143591	43/217 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0388
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810