DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment NitFhit and NIT3

DIOPT Version :9

Sequence 1:	NP_525122.1	Gene:	NitFhit / 38029	FlyBaseID:	FBgn0024945	Length:	460	Species:	Drosophila melanogaster
Sequence 2:	NP_013455.1	Gene:	NIT3 / 851065	SGDID:	S000004343	Length:	291	Species:	Saccharomyces cerevisiae

Alignment Length:	296	Identity:	99/296 - (33%)
Similarity:	160/296 - (54%)	Gaps:	27/296 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 MSVQKRKDQSATIAVGQMRSTS-DKAANLSQVIELVDRAKSQ--NACMLFLPECCD--FVGESRT 82
            ||..|...|...:|:.|:..:| ||.|||.:....::||..:  :..::.||||.:  :..:...
Yeast     1 MSASKILSQKIKVALVQLSGSSPDKMANLQRAATFIERAMKEQPDTKLVVLPECFNSPYSTDQFR 65

  Fly    83 QTIELSEGLDGELMAQY-RELAKCNKIWISLGGVHERND---QKIFNAHVLLNEKGELAAVYRKL 143
            :..|:....:.....|: ..||...|| |.:||.....|   .||:|..::.||.|:|...:||:
Yeast    66 KYSEVINPKEPSTSVQFLSNLANKFKI-ILVGGTIPELDPKTDKIYNTSIIFNEDGKLIDKHRKV 129

  Fly   144 HMFDVTTKE-VRLRESDTVTPGYCLER--PVSTPVGQIGLQICYDLRFAEPAVLLRKLGANLLTY 205
            |:|||.... :...||:|::||   |:  .:.|..|:.|:.||||:||.|.|:|..:.||..:.|
Yeast   130 HLFDVDIPNGISFHESETLSPG---EKSTTIDTKYGKFGVGICYDMRFPELAMLSARKGAFAMIY 191

  Fly   206 PSAFTYATGKAHWEILLRARAIETQCFVVAAA-----QIGWHNQKRQSWGHSMIVSPWGNVLADC 265
            ||||...||..||.:|.|:||::.|.:|:..:     |..:|     ::|||::|.|.|.::|:.
Yeast   192 PSAFNTVTGPLHWHLLARSRAVDNQVYVMLCSPARNLQSSYH-----AYGHSIVVDPRGKIVAEA 251

  Fly   266 SEQELDIGTAEVDLSVLQSLYQTMPCFEHRRNDIYA 301
            .|.| :|..||:|..|::|..|.:|..:.||.|:|:
Yeast   252 GEGE-EIIYAELDPEVIESFRQAVPLTKQRRFDVYS 286

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
NitFhit	NP_525122.1	nit	34..296	CDD:143596	91/278 (33%)
NitFhit	NP_525122.1	FHIT	317..436	CDD:238606
NIT3	NP_013455.1	nit	12..281	CDD:143596	91/278 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0388
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810