DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment NitFhit and Hint3

DIOPT Version :9

Sequence 1:	NP_525122.1	Gene:	NitFhit / 38029	FlyBaseID:	FBgn0024945	Length:	460	Species:	Drosophila melanogaster
Sequence 2:	XP_006512886.1	Gene:	Hint3 / 66847	MGIID:	1914097	Length:	200	Species:	Mus musculus

Alignment Length:	145	Identity:	29/145 - (20%)
Similarity:	53/145 - (36%)	Gaps:	41/145 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   325 KRTIFY-ESEHCFAFTNLRCVVKGHVLVSTKRVTPRLCGL--DCAEM-------ADMFTTV---- 375
            |..:|: |:|....|.:::.....|.||..|:.......|  |..||       ..:||.|
Mouse    43 KTELFHCENEDLVCFKDIKPAALYHYLVVPKKHIGSCKDLNKDHIEMVYSRSVLVAVFTRVWVSL 107

  Fly   376 CLVQRLLEKIYQTTSATVTVQDGAQAGQT------------------------VPHVHFHIMPRR 416
            .::...|::|.:|  ....|:....||:|                        :.|:|.|:: ..
Mouse   108 AVLYGTLQRINET--RLFRVESMVAAGKTMLERNNFTDFTDVRMGFHVPPFCSISHLHLHVI-AP 169

  Fly   417 LGDFGHNDQIYVKLD 431
            :.:||...::..:.|
Mouse   170 VKEFGFLSKLVYRQD 184

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
NitFhit	NP_525122.1	nit	34..296	CDD:143596
NitFhit	NP_525122.1	FHIT	317..436	CDD:238606	29/145 (20%)
Hint3	XP_006512886.1	aprataxin_related	30..168	CDD:238609	26/127 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0537
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810