Protein Alignment NitFhit and NIT2

DIOPT Version :10

• Sequence 1: NP_525122.1
• Gene: NitFhit / 38029
• FlyBaseID: FBgn0024945
• Length: 460
• Species: Drosophila melanogaster
• Sequence 2: XP_054203250.1
• Gene: NIT2 / 56954
• HGNCID: 29878
• Length: 381
• Species: Homo sapiens
• Alignment Length: 269
• Identity: 94/269 - (34%)
• Similarity: 153/269 - (56%)
• Gaps: 4/269 - (1%)

  Fly    35 IAVGQMRSTSDKAANLSQVIELVDRAKSQNACMLFLPECCDFVGESRTQTIELSEGLDGELMAQY 99
            :|:.|::.:|.|:.|:::....:..|.:|.|.::.||||.:....:: ...|.:|.:.||...:.
Human   111 LALIQLQISSIKSDNVTRACSFIREAATQGAKIVSLPECFNSPYGAK-YFPEYAEKIPGESTQKL 174

  Fly   100 RELAKCNKIWISLGGVHERNDQKIFNAHVLLNEKGELAAVYRKLHMFDVTTK-EVRLRESDTVTP 163
            .|:||...|::..|.:.|.:..|::|...:....|.|.|.|||:|:||:... ::..:||.|::|
Human   175 SEVAKECSIYLIGGSIPEEDAGKLYNTCAVFGPDGTLLAKYRKIHLFDIDVPGKITFQESKTLSP 239

  Fly   164 GYCLERPVSTPVGQIGLQICYDLRFAEPAVLLRKLGANLLTYPSAFTYATGKAHWEILLRARAIE 228
            |.... ...||..::||.||||:||||.|.:..:.|..||.||.||...||.||||:|.|:||::
Human   240 GDSFS-TFDTPYCRVGLGICYDMRFAELAQIYAQRGCQLLVYPGAFNLTTGPAHWELLQRSRAVD 303

  Fly   229 TQCFVVAAAQIGWHNQKRQSWGHSMIVSPWGNVLADCSEQELDIGTAEVDLSVLQSLYQTMPCFE 293
            .|.:|..|:..........:||||.:|:|||.|||....:|. |..:::||..|..:.|.:|.|.
Human   304 NQVYVATASPARDDKASYVAWGHSTVVNPWGEVLAKAGTEEA-IVYSDIDLKKLAEIRQQIPVFR 367

  Fly   294 HRRNDIYAL 302
            .:|:|:||:
Human   368 QKRSDLYAV 376

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NitFhit	NP_525122.1	nit	34..296	CDD:143596	90/261 (34%)
		FHIT	317..436	CDD:238606
NIT2	XP_054203250.1	nit	110..370	CDD:143596	90/261 (34%)