DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment NitFhit and Nit2

DIOPT Version :9

Sequence 1:	NP_525122.1	Gene:	NitFhit / 38029	FlyBaseID:	FBgn0024945	Length:	460	Species:	Drosophila melanogaster
Sequence 2:	NP_075664.1	Gene:	Nit2 / 52633	MGIID:	1261838	Length:	276	Species:	Mus musculus

Alignment Length:	279	Identity:	96/279 - (34%)
Similarity:	152/279 - (54%)	Gaps:	9/279 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 IAVGQMRSTSDKAANLSQVIELVDRAKSQNACMLFLPECCDFVGESRTQTIELSEGLDGELMAQY 99
            :|:.|::.:|.|:.||::...||..|..|.|.::.||||.: .....|...:.:|.:.||...:.
Mouse     6 LALIQLQVSSIKSDNLTRACSLVREAAKQGANIVSLPECFN-SPYGTTYFPDYAEKIPGESTQKL 69

  Fly   100 RELAKCNKIWISLGGVHERNDQKIFNAHVLLNEKGELAAVYRKLHMFDVTTK-EVRLRESDTVTP 163
            .|:||.:.|::..|.:.|.:..|::|...:....|.|...:||:|:||:... ::..:||.|::|
Mouse    70 SEVAKESSIYLIGGSIPEEDAGKLYNTCSVFGPDGSLLVKHRKIHLFDIDVPGKITFQESKTLSP 134

  Fly   164 GYCLERPVSTPVGQIGLQICYDLRFAEPAVLLRKLGANLLTYPSAFTYATGKAHWEILLRARAIE 228
            |.... ...||..::||.||||:||||.|.:..:.|..||.||.||...||.||||:|.||||::
Mouse   135 GDSFS-TFDTPYCKVGLGICYDMRFAELAQIYAQRGCQLLVYPGAFNLTTGPAHWELLQRARAVD 198

  Fly   229 TQCFVVAAAQIGWHNQKRQSWGHSMIVSPWGNVLADCSEQELDIGTAEVDLSVLQSLYQTMPCFE 293
            .|.:|..|:..........:||||.:|.|||.||.....:| .|..:::||..|..:.|.:|..:
Mouse   199 NQVYVATASPARDDKASYVAWGHSTVVDPWGQVLTKAGTEE-TILYSDIDLKKLAEIRQQIPILK 262

  Fly   294 HRRNDIYALTAYNLRSKEP 312
            .:|.|:     |.:.||:|
Mouse   263 QKRADL-----YTVESKKP 276

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
NitFhit	NP_525122.1	nit	34..296	CDD:143596	90/261 (34%)
NitFhit	NP_525122.1	FHIT	317..436	CDD:238606
Nit2	NP_075664.1	nit	5..265	CDD:143596	90/261 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0388
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1154369at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820