DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment NitFhit and CG8132

DIOPT Version :9

Sequence 1:	NP_525122.1	Gene:	NitFhit / 38029	FlyBaseID:	FBgn0024945	Length:	460	Species:	Drosophila melanogaster
Sequence 2:	NP_649888.1	Gene:	CG8132 / 41121	FlyBaseID:	FBgn0037687	Length:	283	Species:	Drosophila melanogaster

Alignment Length:	275	Identity:	96/275 - (34%)
Similarity:	156/275 - (56%)	Gaps:	15/275 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 IAVGQMRSTSDKAANLSQVIELVDRA-KSQNACMLFLPECCDFVGESRTQTI-ELSEGL-DGELM 96
            :|:.|::.:.||.||:...:..::.| |.....::.||||  |.....|:.. |.||.: ||...
  Fly    10 LALLQLKGSKDKVANVQNAVTKIEAAVKEHKPRLITLPEC--FNAPYGTKYFREYSETIPDGYTS 72

  Fly    97 AQYRELAKCNKIWISLGGVHE--RNDQKIFNAHVLLNEKGELAAVYRKLHMFDVTTK-EVRLRES 158
            .|...||:.::::|..|.:.|  .|| .|:|...:.:..|:|.|.:||:|:||:..| .:|.:||
  Fly    73 QQLSNLARKHQVYIVGGTIPELGEND-AIYNTCTVWSPTGDLVAKHRKMHLFDIDVKGGIRFKES 136

  Fly   159 DTVTPG--YCLERPVSTPVGQIGLQICYDLRFAEPAVLLRKLGANLLTYPSAFTYATGKAHWEIL 221
            :|::.|  :.:   ::....:||:.||||:||.|.|.|.|..|..::.||:||...||..|||:|
  Fly   137 ETLSAGNDFTI---INVDGHKIGIGICYDIRFEEMARLYRNAGCEMIIYPAAFNMTTGPLHWELL 198

  Fly   222 LRARAIETQCFVVAAAQIGWHNQKRQSWGHSMIVSPWGNVLADCSEQELDIGTAEVDLSVLQSLY 286
            .|:||.:.|.|||..:.....:.:..::||||:|:||..|....||.| :|..|::|.|.::.:.
  Fly   199 QRSRANDNQLFVVTTSPARDTSAEYVAYGHSMVVNPWAKVQQSASEGE-EIVVADIDFSEVEQVR 262

  Fly   287 QTMPCFEHRRNDIYA 301
            |.:|.|..||.|:||
  Fly   263 QQIPVFGQRRLDLYA 277

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
NitFhit	NP_525122.1	nit	34..296	CDD:143596	91/268 (34%)
NitFhit	NP_525122.1	FHIT	317..436	CDD:238606
CG8132	NP_649888.1	nit	9..272	CDD:143596	91/268 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45466370
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0388
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1154369at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm51442
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR23088
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	6	5.850