DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment NitFhit and pyd3

DIOPT Version :9

Sequence 1:	NP_525122.1	Gene:	NitFhit / 38029	FlyBaseID:	FBgn0024945	Length:	460	Species:	Drosophila melanogaster
Sequence 2:	NP_649732.1	Gene:	pyd3 / 40916	FlyBaseID:	FBgn0037513	Length:	386	Species:	Drosophila melanogaster

Alignment Length:	235	Identity:	49/235 - (20%)
Similarity:	92/235 - (39%)	Gaps:	43/235 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    74 CDFVGESRTQTIELSEGLDGELMAQYRELAKCNKIWISLGGVHER---NDQKIFNAHVLLNEKGE 135
            |:|..|:.          :|.......||||...: :.:..:.||   :.:.|:|..|:::..|.
  Fly   137 CEFAEEAE----------NGPTTKMLAELAKAYNM-VIIHSILERDMEHGETIWNTAVVISNSGR 190

  Fly   136 LAAVYRKLHM-----FDVTTKEVRLRESDTVTPGYCLERPVSTPVGQIGLQICYDLRFAEPAVLL 195
            ....:||.|:     |:.:|..:   |.:|..|.:      .|..|::.:.|||.....:..::.
  Fly   191 YLGKHRKNHIPRVGDFNESTYYM---EGNTGHPVF------ETEFGKLAVNICYGRHHPQNWMMF 246

  Fly   196 RKLGANLLTYPSAFTYATGKAHWEILLRARAIETQCFVVAAAQIGW---------------HNQK 245
            ...||.::..|||......:..|.|..|..||....|.|...::|.               |.:.
  Fly   247 GLNGAEIVFNPSATIGRLSEPLWSIEARNAAIANSYFTVPINRVGTEQFPNEYTSGDGNKAHKEF 311

  Fly   246 RQSWGHSMIVSPWGNVLADCSEQELDIGTAEVDLSVLQSL 285
            ...:|.|.:.:|.|:.....|..:..:...|:||::.:.:
  Fly   312 GPFYGSSYVAAPDGSRTPSLSRDKDGLLVVELDLNLCRQV 351

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
NitFhit	NP_525122.1	nit	34..296	CDD:143596	49/235 (21%)
NitFhit	NP_525122.1	FHIT	317..436	CDD:238606
pyd3	NP_649732.1	PLN00202	9..385	CDD:177792	49/235 (21%)
pyd3	NP_649732.1	ML_beta-AS	9..372	CDD:143611	49/235 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45466371
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0388
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.740