DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment NitFhit and nit2

DIOPT Version :9

Sequence 1:	NP_525122.1	Gene:	NitFhit / 38029	FlyBaseID:	FBgn0024945	Length:	460	Species:	Drosophila melanogaster
Sequence 2:	NP_991174.3	Gene:	nit2 / 402904	ZFINID:	ZDB-GENE-050522-65	Length:	284	Species:	Danio rerio

Alignment Length:	272	Identity:	97/272 - (35%)
Similarity:	150/272 - (55%)	Gaps:	6/272 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 IAVGQMRSTSDKAANLSQVIELVDRAKSQNACMLFLPECCDFVGESRTQTI-ELSEGLDGELMAQ 98
            :||.|:..:..||.||.:...||..|..|.|.::.||||  |.....|... |.:|.:.||....
Zfish    13 LAVVQLHVSKIKADNLGRAQTLVTEAAGQGAKVVVLPEC--FNSPYGTGFFKEYAEKIPGESTQV 75

  Fly    99 YRELAKCNKIWISLGGVHERNDQKIFNAHVLLNEKGELAAVYRKLHMFDVTTK-EVRLRESDTVT 162
            ..|.||...|::..|.:.|.:..|::|...:....|:|...:||:|:||:... ::|.:||:|::
Zfish    76 LSETAKKCGIYLVGGSIPEEDGGKLYNTCSVFGPDGKLLVTHRKIHLFDIDVPGKIRFQESETLS 140

  Fly   163 PGYCLERPVSTPVGQIGLQICYDLRFAEPAVLLRKLGANLLTYPSAFTYATGKAHWEILLRARAI 227
            ||..|.. ..||..::|:.||||:||||.|.:..|.|..||.||.||...||.||||:|.|.||:
Zfish   141 PGKSLSM-FETPYCKVGVGICYDIRFAELAQIYAKKGCQLLVYPGAFNMTTGPAHWELLQRGRAV 204

  Fly   228 ETQCFVVAAAQIGWHNQKRQSWGHSMIVSPWGNVLADCSEQELDIGTAEVDLSVLQSLYQTMPCF 292
            :.|.:|..|:..........:||||.:::|||.|::....:| .:..|::||..|..:.|.:|..
Zfish   205 DNQVYVATASPARDETASYVAWGHSSVINPWGEVISKAGSEE-SVVYADIDLQYLADVRQQIPIT 268

  Fly   293 EHRRNDIYALTA 304
            :.||||:|::.:
Zfish   269 KQRRNDLYSVNS 280

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
NitFhit	NP_525122.1	nit	34..296	CDD:143596	92/262 (35%)
NitFhit	NP_525122.1	FHIT	317..436	CDD:238606
nit2	NP_991174.3	nit	12..272	CDD:143596	92/262 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0388
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1154369at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.820