Protein Alignment NitFhit and Btnd

DIOPT Version :10

• Sequence 1: NP_525122.1
• Gene: NitFhit / 38029
• FlyBaseID: FBgn0024945
• Length: 460
• Species: Drosophila melanogaster
• Sequence 2: NP_572298.1
• Gene: Btnd / 31552
• FlyBaseID: FBgn0029848
• Length: 553
• Species: Drosophila melanogaster
• Alignment Length: 553
• Identity: 105/553 - (18%)
• Similarity: 190/553 - (34%)
• Gaps: 157/553 - (28%)

  Fly    11 SIVIAIHQQLRRMSVQKRKDQSATIAV---GQMRSTSDKAANLS---------------QVIELV 57
            |::.:...||     .|.:|.:.|.||   .|....|.:|...|               .:|...
  Fly    12 SVLFSSSHQL-----SKPEDPTYTAAVVEHSQPVGDSPRARTTSASESFQKIIREVGDVDIIVFP 71

  Fly    58 DRAKSQNACMLFLPECCDFVGESRTQTIELSEGLDGEL-MAQYRELAKCNKIWISLGGVHER--- 118
            :...:..|...|:|.        .:|.|......|.|| :.:....|:.|.:::.:..|.:.
  Fly    72 EHILNSQATATFVPH--------ESQNITPCYQTDYELFLIELSCSARANHLYVVINVVEKELCA 128

  Fly   119 -------------NDQKIFNAHVLLNEKGELAAVYRKLHMFD---VTTKEVRLRESDTVTPGYCL 167
                         :..:.||.:|:.:.:|.:.:.|||.|::.   |:|..:|       :|...:
  Fly   129 HGAGSDTYNPCPSSGVRYFNTNVVFDRRGRIVSRYRKTHLWRHEYVSTSVLR-------SPDISI 186

  Fly   168 ERPVSTPVG-QIGLQICYDLRFAEPAV-LLRKLGANLLTYPSAFTYATGKAHWEILLRARAIETQ 230
            .|   |..| ..|..||:|:.|.:||: |:::.....:.||:         :|         .::
  Fly   187 FR---TDFGVTFGHFICFDMLFYDPAMKLVKEHKITDIVYPT---------YW---------FSE 230

  Fly   231 CFVVAAAQI--GW-------------HNQKRQSWGHSMIVSPWGNVLADCSEQ-ELDIGTAEVDL 279
            ...:.|.|:  ||             .|...::.|..:.....|.::|:..|| ...:..|||..
  Fly   231 LPFLGAVQLQEGWAFGNDVNVLAADASNPDGRTSGSGIYAGRGGRLVAEIFEQPTTKLLIAEVPK 295

  Fly   280 SVLQSLYQTM-PCFEHRRND--IYALTAYNLRSKEPTQDRPFATNIVDKRTIFYESEHCFAFTNL 341
            .....|..|. |.||.:|..  :..|..|...:.:     .|.:.::|...:.:|.:.|......
  Fly   296 REHGQLAPTFTPIFEPQRKTQRLTGLATYRDNNVD-----IFESELLDDDFLSFERQLCHGSFCC 355

  Fly   342 RCVVKGHVLVSTKRVTP-------------------RLCGLDCAEMADMFTTVCLVQRLL----- 382
            ...::..|..:.:...|                   .:.|:|..|.|......|...||.
  Fly   356 TFSIERKVTSAAENELPSSGAKSYRYRIGVYWGNETTVIGVDRTEQATCALFACTDVRLASCGYI 420

  Fly   383 ----EKIYQTTSATVTVQDG----AQAGQTVPHVHFHIMPRRLG----DFGHNDQIYVKLDERAE 435
                |::..|...|.....|    |..|:.:      |||..|.    ....:|..:::..|.|.
  Fly   421 YPENEEVINTHHFTKLSISGNFPAAPRGRRL------IMPSSLNALFLPVSVSDYEWIESPEAAN 479

  Fly   436 EKPPRTI--EERIEEAQ-------IYRKFLTDI 459
            .. .:||  :.::.:||       |:..:.|||
  Fly   480 NL-DKTILVDLKLAKAQNDLLTFAIWANYYTDI 511

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NitFhit	NP_525122.1	nit	34..296	CDD:143596	63/318 (20%)
		FHIT	317..436	CDD:238606	26/154 (17%)
Btnd	NP_572298.1	biotinidase_like	29..308	CDD:143591	60/314 (19%)
		Vanin_C	325..511	CDD:465946	32/197 (16%)